Solubility

Chromatography Abstract: The purpose of this lab is to use chromatography to separate and purify organic compounds. There are many different types of chromatography but most depend on the principle of adsorption. The two important components of chromatography are the adsorbent and the eluent. Adsorbents are usually solid materials that will attract and adsorb the materials to be separated. The eluent is the solvent, which carries the materials to be separated through the adsorbent. After being…

That are unstable*degradable in the intestinal or colonic environment, iv. Have low solubility at high*higher pH values. Gastro retentive Dosage Form (GRDF) 5, 6: It is evident*clear-cut from the recent scientific and patient literature that an increased interest in novel dosage forms that are retained in stomach for a prolonged and predictable…

OBJECTIVE: To deliver lornoxicam into systemic circulation by engineering ethosomal gel formulation. RATIONAL OF WORK: Because of their improved pervasion of medication through skin.  lornoxicam is BCS class II medication causes gastric bothering when managed orally  ethosomes are stages for the conveyance of vast and differing gathering of medications.  due to their generally safe profile.  better understanding agreeability can be utilized as a part of the manifestation of gel,…

2.1.2. Alkaline hydrolysis Alkaline hydrolysis is a simple process in which the protein is solubilized by heating followed by the addition of calcium, sodium or potassium hydroxide as alkaline agents and maintaining the temperature at a range between 25-55 °C (Pasupuleti & Braun, 2010). During alkaline hydrolysis of proteins, some amino acids like serine and threonine are damaged during alkaline hydrolysis, however, tryptophan remains intact. Also, this process causes racemization of amino acids…

charge. Two opposite charges get attracted to each other and that is how the Iron was attracted to the Magnet. When it comes to the separation of Sand and Sodium chloride, they were separated because of the unique property of Sodium Chloride which is solubility. When the mixture of Sand and Sodium chloride was mixed in the water, the sodium chloride had the capacity of being dissolved in the water leaving the sand undissolved. When the mixture was filtered using a filer paper, the Sodium…

separation, mechanisms, acid-base reactions, evaporation, recrystallization, and identification. The goal of this experiment was to identify the unknown mixture of two compounds. The two compounds were separated first by altering the acid components solubility through deprotonation, and then protonating the acid component again to form the separated precipitate. The ether in the neutral layer was evaporated, and the residue was recrystallized. The crystals were subject to a melting point…

from the distillate. It will then be evaporated leaving behind the pure compound. Reactions: Cinnamaldehyde Chemical Formula: C9H8O Molar mass: 132.16g/mol Appearance: Yellow oil Odor: cinnamon-like Density: 1.0497 g/ml Boiling point: 248 oC Solubility in water: Slightly Soluble Vaporization: (l) (g) Condensation: (g) (l) Extraction: (l) + (l)+ H2O(l) + Na2SO4(s) (s) +Na2SO4ˑ10H¬2O(s) + CH2Cl2(g) Procedure: Reference: Poulos, Zacary J. A Laboratory Manual for the Health…

N-Vinyl pyrrolidone (NVP) and its copolymers attracting much attention and have been widely investigated for applications in different field due to its low toxicity, biocompatibility and good film forming (Hemalatha et al. 2014; Anasuya; Lee et al. 2007). The amide group in NVP is highly polar, which confirms it’s hydrophilic. NVP has been copolymerized with various monomers because the amide group has high affinity for many large and small molecules that are known to be good hydrogen-bond…

Introduction Extraction involves the separation of compounds in a mixture. This separation in based on the differences in each compound’s solubility. For the purpose of this lab, the liquid-liquid extraction technique was used. This method involves using two immiscible solvents, and because of each compounds solubility in each of those solvents, the mixed compounds can separate. Generally, this process includes water as one of the immiscible solvents, but for this lab, t-butyl methyl ether was…

They are the basic and universally acceptable factors put into consideration for examination of drug product development. Physiochemical nature of the drug, rate of solubility and dissolution rate of the drug are essential Biopharmaceutical factors considered in drug product development. It provides the scientific platform for drug product design and development. These factors if maintained and controlled ensures that…