In conclusion, we reported the synthesis of fused and isolated triazoles based on thieno[2,3-d]pyrimidines. The synthesized 1,2,4-triazolo compounds were screened for their anticancer activity at a concentration of 10 μΜ against a panel of 60 cell lines derived from nine different types of cancers, and also screened for their PDE 5 inhibitory activity. The possibility of combining 1,2,4-triazolo moiety to thieno[2,3-d]pyrimidines should open new opportunities for the rational design of…
identifying reducing sugars, which are simple sugars that include monosaccharides and some disaccharides. The Benedict’s reagent is made of Copper (II) sulfate ion which reduces to Copper (I) during the test. It is made by adding copper sulfate with sodium citrate and carbonate that is dissolved in 400mLs of water (Benedict’s Test). The chemical reaction within this test is…
sensation, muscle contraction, hormonal activity, fluid secretion, immune response and, of course, brain activity. Ion channel drugs are used to treat major cardiovascular, neurological, muscular, metabolic, and respiratory conditions. In particular, sodium channel drugs have the remarkable ability to target specific cells to control sensory or motor functions, without threatening vital processes. This selectivity allows for uses as local anaesthetic, analgesic, anti-arrhythmic and…
There are so many chemical reactions and it is important to classify a chemical reaction to understand the reaction and predict the products. In this lesson, we will discuss the definition and go over examples of a combination reaction. !!!What is a Combination Reaction? Putting furniture together, combining ingredients to make something delicious – these things can be fun activities and we look forward to the results. Each individual component is not very exciting by itself. However, if we…
oxide that works as both an acid or a base. Thus, the reaction resulted in the production of a murky coloured liquid. If a full neutralization reaction was to completed, a product of a transparent solution should have been created. Sodium phosphate and potassium sodium tartrate are both not strong bases and that is why the average pH change was quite low. Both of them are not bases, however, they have a high pH. This is why they were both able to increase the pH on the acidic solution. A…
confetti? Taking after are the brief delineations of use of MSG: • Meat, Poultry and Fish MSG can be used as a piece of meat, poultry and fish as sodium or potassium lactate to open up time range of ease of use, control pathogenic microorganisms (improve food wellbeing), overhaul and secure meat flavor, upgrade water tying constrain and reduce sodium. • Beverages In light of its delicate taste, MSG is used as a destructiveness controller as a piece of refreshments, for instance, pop pops…
It is well known that all organisms require at least some water to survive, even the most hardy creature on the planet earth, the tardigrade, Hypsibius dujardini, which can survive near complete dehydration, exposure to extreme radiation, vacuum, temperature and pressure, must be rejuvenated with water if it is to resume life after near complete desiccation (Gabriel, et al. 2007). H. dujardini, famous for surviving some of the harshest conditions of any organism we know of, is a perfect example…
initial hypothesis. However, I believe the data would be more consistent and solid had 2M and 4M of NaCl had been included in the experiment, rather than jumping from 1M to 3M to 5M. Discussion: For this lab experiment, the independent variable is the sodium chloride, as it was the variable being manipulated throughout the course of the experiment. The dependent variable is the boiling point temperature, as it was the variable being measured. The experimental control is the water that received…
The first mixture of sodium chloride and water is homogenous the salt equally spreads out when added to the water. After adding sand, the second mixture becomes heterogeneous, the sand sinks to the bottom of the beaker and does not mix among the salt and water. b. The mixture…
During the experiment, observations were made about their physical appearance. In part I, reaction one produced a blinding, bright white light when the metal burned and the metal turned into a white powdery substance. For reaction two, there was no reaction at first and it took a long time for it to react, but then bubbles started to form around the magnesium ribbon and the substance turned into a pink-yellowish color around the magnesium strip when it was placed in the 150 milliliters beaker.…