Simvastatin

Title: The risk of diabetes mellitus among statin users: A disproportionality analysis using FAERS data Authors: Ajinkya Pawar, BS1 1College of Pharmacy, University of Rhode Island, Kingston, RI Objective: To evaluate diabetes mellitus adverse events reported for the statin use. ¬ Background : Statins, a class of medications prescribed to reduce blood levels of LDL cholesterol, have been found to increase the risk of developing diabetes mellitus (DM).1 Such association has been observed in…

Key Issues of Concern This is Mrs. H, a 70-year-old African American female presented to the clinic with complex health problems. Some of her problems include: hypertension, heart failure. Patient has genetic predisposition to some diseases like DM2, hyperlipidemia, and hypertension. This could be a contributing factor to her health problems. She has diabetes with an A1c of 8.5, this indicates that her diabetes is not within the normal range of less than 7% (National Guideline Clearinghouse,…

Drug Rash Skin reactions can be caused by several different drugs. Allergy to the medicine can cause itching, hives, and other rashes. Sun exposure causes a red rash with some medicines. Mononucleosis virus can cause a similar red rash when you are taking antibiotics. Sometimes, the rash may be accompanied by pain. The drug rash may happen with new drugs or with medicines that you have been taking for a while. The rash cannot be spread from person to person. In most cases, the symptoms of a…

Priority Medications The person I interviewed is a 70 year old man who lives alone, his wife passed away about 4 years ago. He has a history of hypertension and has been taking Lisinopril since 1989. He has high cholesterol and is currently on simvastatin. He had a triple heart bypass in 2005 and was started on carvedilol after the surgery. He also takes aspirin, vitamin D3, calcium and Zoloft. With his cardiac history his top four priority medications are carvedilol,…

Evidence of effectiveness in cost saving of generic drug expansion policies Generic drugs can save healthcare expenditures through three main pathways including generic substitution of drugs, substitution of drugs in the same therapeutic class, and reduction in the average branded prices. First, the largest cost saving comes from the generic substitution of drugs by substituting the less expensive generic drug for the therapeutically equivalent branded drugs. Generic substitution rates are…

Vytorin is a prescription drug that helps with reducing the amount of “bad” cholesterol, known as low density lipoproteins, absorbed by your body with a combination of ezetimibe and simvastatin (Vytorin). The advertisement has pictures of food on the left side and then a picture of a person who looks like the food on the right side which is supposed to represent people in your family (G). They do this in order to show the two main causes of increased cholesterol. By the end of the commercial you…

thinners or insulin. We will need to obtain records to confirm this. She was diagnosed with HTN about 4 months after her last pregnancy and she has been on medication. Currently coming into pregnancy, she is on HCTZ and atenolol. She also takes simvastatin for…

is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits. Example drugs: atorvastatin, simvastatin, warfarin, methotrexate, finasteride Class ( N): FDA has not classified the drug. Example drugs: aspirin, oxycodone, hydroxyzine, acetaminophen,…

-What are the treatment goals for ARDS? The first object of ARDS treatment is to improve the level of blood oxygen. Without oxygen, your organs may not function properly. In order to get more oxygen into bloodstream, for milder symptoms or as a temporary measure, oxygen may be delivered through a mask that fits tightly over your nose and mouth. Most people with ARDS will need the help of a machine to breathe. A mechanical ventilator pushes air into lungs and forces some of the fluid out of the…

He is currently taking: Metformin HCl tabs 500 mg PO BID and Glipizide XL tabs 2.5 mg PO once a day to control his diabetes; Benazepril HCl tabs 20 mg PO once a day and Amlodipine Besylate tabs 5 mg PO once a day to control his hypertension; and Simvastatin tabs 20 mg PO once a day for hyperlipidemia. Over the past 25 years there have been different medications and treatment plans introduced for J.T.; however, some have caused more harm than good. Thankfully, with the progression of research and…