Simvastatin

Bailey Mehalick Section 3 April 10, 2017 CVS Health Write Up Case Type I believe the CVS: Promoting Drug Adherence case follows the elements of an evaluations case. This case in particular focuses on the decisions made by Foulkes surrounding drug adherence through new programs. Additionally, this case already provides us with the decision CVS chose to make, however, an analysis of this decision is not given and therefore a personal evaluation and analysis is crucial. Ultimately, the question is how to enhance the Pharmacy Advisor Program to achieve better results in the future. Problem Statement The problem statement for this case asks how Foulkes can show to the company’s stakeholders how investing in adherence would have a valuable and positive impact on CVS Health’s profitability. What made this challenging was CVS Health’s unique company structure which requires them to find a balance between helping the pharmacy benefit manager (PBM) clients save while also providing plan members with access to reasonably priced medications and health outcomes. Calculate the dollar value to the additional adherence that comes from the Pharmacy Advisor Program to CVS per patient. In doing so, show your calculations. High Cholesterol: 0.5% adherence increase + 30% increase from phone calls 1,860*1.305= $2,444 $584 savings per patient Diabetes: 1.4% adherence increase + 30% increase from phone calls 4,413*1.314= $5,799 $1,386 savings per patient Depression: 0.4% adherence increase +…

When the concentration of simvastatin becomes too high for the body, the drug can be toxic to the body (Lynn, 2012). OBJECTIVE #5 - Alternate treatment choices that would have avoided this serious adverse drug event • The physician may have prescribed a variety of alternative antibiotics to treat Saskia’s pneumonia to eliminate drug-drug interactions that occurred with her current medications. The antibiotic prescribed cannot inhibit the CYP3A4 isoenzyme because it allows simvastatin to be…

Aspartate transaminase (1030 U/L) o Elevated levels since normal values (in females) should be between 8-40 U/L ♣ Indicates that the patient is experiencing acute kidney injury (Devaraj 2015) Objective 3: The potential for any drug – drug interactions that may explain the rhabdomyolysis • Simvastatin (for hypercholesteremic) o Causes ALT elevations are cause by liver…

8: Effect of Gum acacia and simvastatin on serum High Density lipoprotein (HDL) levels in triton induced hyper-lipidemic mice. Normal Triton WR1339 Gum Acacia Simvastatin 5% solution 10% solution 20% solution High Density lipoprotein (HDL) (mg/dl) 62.97 39.83 28.6 27.63 30.26 27.51 72.7 52.64 32.23 31.67 40.94 31.3 53.04 27.02 24.97 23.59 19.58 23.72 Table no. 9: Effect of Gum acacia and simvastatin on serum Low Density lipoprotein(LDL) levels in triton induced…

disease (Carroll, Kit, Lacher& Yoon, 2013). Also, Mr. B is very likely to have Type 2 Diabetes because Type2 diabetes is often accompanied by high triglyceride levels, reduced HDL cholesterol, and high LDL levels (Miller et al., 2011). Question 5. What is the purpose of Simvastatin, why has it been prescribed for Mr. B? Simvastatin is a stain medication which is prescribed to treat dyslipidaemia, such as hypercholesterolaemia, mixed hyperlipidaemia, and prevent coronary heart disease…

its moiety composed of a ring system with diverse substituents. Different statin groups can have certain differences in the structure, which in turn governs their water solubility and influences their absorption, distribution, metabolism and excretion. Upon oral administration all statins are well absorbed from the intestine, albeit extensive first-pass metabolism occurs in the liver with the subsequent reduction of systemic bioavailability from 5 to 50%. Most statins are administered as…

Background: Atrial fibrillation (AF) is the most common coronary artery bypass graft (CABG) post-op arrhythmia. This complication can increase the patient’s chances for a longer hospital stay, stroke, or death; resulting in additional healthcare costs. Prescribing statins (3-hydroxy-3-methylglutaryl COA reductase inhibitors) to reduce the risk of postoperative AF (POAF) is well studied, as they provide anti-inflammatory and antioxidant benefits within hours of initiation. However, whether the…

DOI: 11/1/2000. The patient is a 60-year-old male sales representative who sustained injury while he was grabbing a ladder to get samples and felt pain in his back. Patient is status post L5-S1 intradiscal electrothermal therapy procedure and L5-S1 fusion on 04/30/13. Urine drug screen obtained on 03/16/15 showed positive for hydrocodone, hydromorphone, dihydrocodeine, norhydrocodone, carisoprodol and meprobamate. As per progress report dated 6/8/2016, patient’s medications include Pulmicort,…

work in all 5 borough and the pre-screening was scheduled 11-9-2016 @ 1pm at 123 William St, 6th Floor, New York, New York. Client continues to report she just received the letter yesterday but she is not interested. She also received a Recertification Questionnaire/for Eligibility and CM assisted the client to fill out the form. Client continues to reports chronic arthritis in her back, neck and leg, sleep apnea, hemorrhoid flare up and asthmas and receives medical services at Union Community…

at some high risk because of his many health complications and age, but currently the risks are not as beneficial as the therapeutic effects of the drug. Special precautions should be made if were to suffer from or develop any of the following conditions: cardiogenic shock, sever sinus node dysfunction, 2nd and 3rd AV block, or bradycardia. (Nursing Central) Drug-Drug Interactions Amiodarone currently interacts with the following medication: fluoroquinolones, macrolides, antifungals,…