Silent Hill 2

Problem Statement Diabetes is a health issue with an increasing rate of diagnosed cases in many communities in the United States. Type II occurs when the pancreas can’t produce enough insulin and lack the ability to take in insulin. It leads to a higher reading of glucose levels, which increases the risk of metabolic complications throughout one’s life (NDEP-“The Diabetes Epidemic”, n.d.). Epidemiology While diabetes most prominently affects the Hispanic/Latino community, it is only in the…

Clinical development Clinical study background Alogliptin (Nesina®) is a new drug for the treatment of adult patients with type 2 diabetes (T2D) by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme and thereby prevent degradation of incretin hormones [1]. There were a number of clinical evidences for this DPP-4 inhibitor drug to define its use in treating T2D, including the clinical phase I, clinical phase II and III studies, but this review only detailed descripted some typical clinical…

What causes type 2 diabetes? Eating too much and exercising too little can increase the risk for developing type 2 diabetes. Insulin is a hormone made in the pancreas, which allows glucose (sugar) to leave the bloodstream and enter the cells to be used as fuel. Going from type 2 diabetes when the pancreas does not make enough insulin or the body's cells become resistant to insulin. It is not known for sure why some people develop type 2 diabetes and others do not. There are many factors,…

In T1DM, onset of symptoms is often rapid with a characteristic weight loss, excessive thirst, frequent urination, and excessive hunger. To manage the disease, people living with T1DM usually need a supply of insulin from an outside source since the body lacks the ability to produce this hormone. It is important to note that those newly diagnosed with this disease may require less insulin within the first few months of diagnosis because the body is still able to produce some amount of the…

Type 2 diabetes is a condition that is becoming diagnosed more frequently. The risks associated with the condition are not known to everyone, and some believe that diagnosis does not occur until a much older age. However, if left untreated the condition can lead to serious complications, and people have been diagnosed at younger ages every year. With that in mind, the question I propose is what are the different ways a family can work on preventing type 2 diabetes? This research question is…

Diabetes mellitus (DM) can be categorized by a group of metabolic diseases including hyperglycemia resulting from defects in insulin secretion, the action of insulin, or both. In type one DM, the beta cells are completely destroyed in the islets of Langerhans of the pancreas, which leads to insulin deficiency. This can happen at any age, but it mainly occurs before the age of thirty. Type one DM is characterized by hyperglycemia, breakdown of body fats and proteins, and the development of…

Is Diabetes a Family Curse? Diabetes is a serious disease, It was the seventh leading cause of death in the United Sates in 2010, and still remains in the top ten to this day. The cause of the disease is not entirely clear, but according to experts it may be caused by genetic and environmental factors. Furthermore doctors speculate that unlike some traits, diabetes does not seem to be inherited in a simple pattern. However, some people like myself are more likely to develop…

Polycystic ovary syndrome (PCOS) affects up to 10% of women in the reproductive age (1). PCOS is a proinflammatory state characterized by menstrual dysfunction and hyperandrogenism and is associated with features of the metabolic syndrome, particularly, obesity, diabetes, dyslipidemia, and atherosclerosis (1– 4). The metabolic syndrome is associated with excessive accumulation of central body fat. Adipose tissue (AT) produces several cytokines termed adipokines, which have ISSN Print 0021-972X…

2.2 Risk Factors Genetics has a strong impact on atherosclerosis, however only a fraction of cases are due to Mendelian disorders, such as LDL receptor gene mutations. Familial traits that predispose an individual to atherosclerosis include conditions such as, hypertension and diabetes and inflammatory disorders (Crowther, 2005, Falk, 2006, Kumar, 2010). Age also plays a role, as individuals between 40 to 60 years of age are at elevated risk of manifesting atherosclerosis, whilst ischemic heart…

Type 2 Diabetes Increases Risk Factors For Other Medical Conditions Regardless of age or sex, diabetes patients high a higher rate of death versus those who do not. The leading cause of death in diabetics are stroke and heart disease. Therefore, it is important to reduce the risk of these conditions through medical efforts and necessary changes in lifestyle. Type 2 diabetes increases the risk factors for a variety of other medical conditions, including: neuropathy, heart disease, stroke, and…