Signal processing

The Absolutely True Diary of a Part-Time Indian Take Home Test Sherman Alexie’s National Book Award Winning novel, The Absolutely True Diary of a Part-Time Indian, deals with many sensitive issues and topics that teenagers can relate to in their own lives. Dealing with friendships, identity, and bravery, Alexie’s novel constructs an emotional bond with the audience by addressing matters important in a young reader's life. To deprive certain school districts of this piece of literature, is…

1.) There are many reasons why youths may seek out gang involvement. Many gangs offer youth a sense of belonging, via acceptance and gang loyalty which was crucial in the videos. Gangs can provide an identity for their members and a way to acquire a status. This is an attribute to the Social Disorganization/ Sociocultural View according to the text. Using chapter 8 to help guide this point is, children with weak to no ties toward their families, community and or religion may channel their energy…

In this article, the author gathers information on gang members from Mexico, Guatemala, Honduras, and El Salvador, digging deeper into the lives of gangs. The author also gives us a new perspective by adding in many unexpected and surprising statements, including: “The pain,” he said, “seems a small price for a new life. I dream of being clean, even if it means being scarred.” (Quoted by gang member Christian Antunez during a tattoo removal process). By giving us a clear dominant and counter…

Intelligence), which consists of photography or snapshots taken by satellites or reconnaissance planes; MASINT (Measurement and Signature Intelligence), which tracks emissions or “signatures” issued by weapons such as missiles or nuclear warheads; SIGINT (Signals Intelligence), information derived from intercepted electronic communications such as phones, personal computers or radar; HUMINT (Human Intelligence or Espionage)—which is sometimes viewed as the world’s “second oldest profession”…

Topic: Molecular mechanism of dietary restriction in ageing Title: Dietary restriction and mTOR signalling pathway in lifespan extension Dietary restriction (DR), which is reduced intake of all dietary constituents except vitamins and minerals, was first shown to extend the lifespan of rats 80 years ago (McCay, 1930). Since then, many studies have proven that DR can extend longevity on wide range of taxa (Fontana et al., 2010). In addition, research done on animal models reveals that there…

“I refused to fail. I was smart. I was arrogant. I was lucky.” This is a quote from the article “Superman and Me”, that was used by Sherman Alexie. Alexie believed this is what he was and will be. Sherman Alexie was a young Spokane Indian boy that lived on a reservation with the provided needs to live. His family was poor but still managed to obtain all of the necessary essentials. One thing that they had an abundance of was books. The father of Alexie was fascinated with reading, so Alexie…

Lead Identification (LO): Lead compounds bind to target receptors, and shows potentially therapeutic pharmacological activity, and may contain similar structures and functional groups. Lead compounds are used as a foundation for drug development and may be modified structurally for greater pharmacodynamic efficiency and potency.1 One source of determining lead compounds is by assaying libraries through HTS. Researchers analyze the drug’s ADME properties (Absorption, Distribution, Metabolism, and…

Downstream Targets Due to the lack of developing an effective Ras treatment, some have turned to targeting downstream effectors of Ras. Downstream effectors have a critical role in Ras carcinogenesis and are commonly found in KRAS mutated cancers. The most intensely targeted pathways are the Raf-MEK-ERK (MAPK) and PI3K-AKT-mTOR signaling pathways. Raf-MEK-ERK MAPK signaling is initiated through receptor tyrosine kinases after their activation by growth factors (Mccubrey 2006). Once Ras is in its…

Receptors are protein molecules that receive chemical signals in the form of ligands and induce responses at cellular level. They are localized at the cell surface, cytoplasm or the nucleus, depending on their amino acid sequences. In addition to using these three different localizations to categorize receptors, the types of action of receptors are also used as a mean of classification. The four main classifications of receptors are: 1. Ionotropic (or ligand-gated ion channel) receptors, 2.…

According to T.F. Gendron et al., partial amounts of the toxicity are due to a gain in function by the protein. When this occurs, the TDP-43 protein has usually shifted its location from the nucleus to throughout the cytoplasm of the cell. This abnormal accumulation of TDP-43 in the cytoplasm is not only found in neurons and glial cells of the primary motor cortex but as well as in brainstem motor nuclei, the spinal cord, and in certain associated white matter tracts (Mackenzie et al 2010). It…