Sickle

Sickle cell is a disease that affects the circulatory system. The circulatory system is in charge of moving nutrients throughout the entire body with the use of the blood stream. According to hopkinsmedicine.org the circulatory system moves nutrients, water, and oxygen to the your billions of body cells and carries away wastes like; carbon dioxide that body cells create. The circulatory system includes; the heart: which keeps the circulatory system working at all times with its constant…

the recessive gene more often than the homozygous dominant and heterozygous. This is the case with Sickle Cell Anemia, where there is an amino acid substitution, which changes the shape of the protein, causing the cell to sickle.…

Sickle Cell Anemia or also known as Sickle Cell Disease, is a severe hereditary form of anemia in which a mutated form of hemoglobin distorts the red blood cells into a crescent shape at low oxygen levels. When these red blood cells are affected in this way, the irregular shaped cells can get stuck in small blood vessels. If this happens, it can slow or block blood flow and oxygen to parts of the body. Symptoms of this disease easily affect people’s way of life, comfort, and overall…

Understanding the treatment of sickle cell disease with hydroxyurea (HU) is an ever evolving topic as new mechanisms that are affected by HU have and continue to be discovered since it became the only FDA-approved drug for this disease. However, there are many physicians around the world that underutilize this drug. While it may be due to the potential adverse effects that are associated with the use of HU, education on all the affected mechanisms may sway the physicians thinking if they can be…

Sickle Cell Anemia is a blood disorder that causes red blood cells to become misshapen and not live as long as a regular blood cell. Sickle Cell is a disease that is not very common in the world. In the United States, Sickle Cell Anemia affects between 70,000 and 100,000 people and occurring in 1 out of every 36,000 births. Sickle Cell is more likely to occur in somebody from Africa, South or Central America, the Caribbean islands, Mediterranean countries, India or Saudi Arabia. The usual age…

Sickle Cell Anaemia In this essay Sickle Cell Anemia will be investigated in depth. What causes it, how it is passed on from generation to generation, and it’s origin will be explored, along with it’s how it occurs, how often it occurs and whether or not some races are more susceptible to it. Statistics and mortality rates will be included as well as some treatments and suggestions for those suffering with the disorder. Sickle Cell Anemia can lead to many painful side effects of varying…

Inherited red blood cell disorders are grouped together and called Sickle Cell Disease (SCD). Among these disorders, the most severe is Sickle Cell Anemia (HbSS). This red blood cell disorder is inherited and affects the RBC’s ability to carry oxygen (Addis, 2010). Normal red blood cells are disc shaped, but in sickle cell anemia the cells are shaped differently. Red blood cells in clients with Sickle Cell Anemia are sickle-shaped, crescent shaped (Allen & Harper, 2014). These abnormally…

Sickle Cell Disorder [ICD-10 D57] Sickle Cell Disorder (SCD) may be one cause to this child’s previously listed symptoms. SCD is an inherited disease in which an abnormal hemoglobin S [HbS] leads to chronic hemolytic anemia, pain, and organ failure (Grossman & Porth, 2014). SCD is transmitted by a recessive gene and can manifest as a sickle cell trait or sickle cell disease. The sickle cell trait may manifest as a heterozygote with one HbS gene [HbS], and SCD may manifest as a homozygote with…

Sickle cell anemia is a disease that results in the destruction of the protein hemoglobin. Hemoglobin is a molecule located in the red blood cells that is responsible for the delivery of oxygen to the cells to the entire human body. This disease is a reaction of a point mutation in the β-hemoglobin gene that leads to the synthesis of sickle hemoglobin, which distorts and injures the red blood cell (Solovieff, Hartley, Baldwin, Klings, Gladwin, Taylor, & Sebastiani, 2011). Healthy red blood cells…

B. Why is the incidence of sickle-cell anemia an excellent example of a "balanced polymorphism," in which two or more alleles are maintained by natural selection in a population? Balanced polymorphism is the term given to the phenomenon where two different versions of a gene are allowed to coexist in an environment. Sickle cell anemia is a great example of balanced polymorphism in action because when a host with a gene for normal hemoglobin and a gene for sickle hemoglobin is infected with a…