Sickle-cell disease

Sickle -cell anemia is a disease that affects the shape of red blood cells and it causes them to become a sickle shape. Sickle cell anemia was first noticed around 1670, in a tribe called Krobo in Ghana, Africa. In 1910 a physician in Chicago named James Herrick was the first person to first describe it clinically (Kiple). Since then much more information has been discovered on this disease. Such as this is a disease that people inherit from their parents if both are carriers. There are many…

More than 70,000 people in the United States have been affected with Sickle Cell Anemia. Sickle Cell disease is a genetic disorder that affects the red blood cells. The symtopms of the disease was first seen in 1904. The normal doughnut shape of the red blood cells become sickled making it difficult for these cells to transport oxygen throughout the body causing blockages resulting in extreme pain during a crisis. This diseases tends to affect african americans more than any other race, but…

Sickle Cell Anemia is an inherited blood disorder that mostly affects people of African ancestry, but it can also occur in other ethnic groups such as Middle East and Mediterranean descent (National Institute of Health). The disease affects the hemoglobin molecule in the red blood cells. Hemoglobin helps with carrying oxygen from the lungs and delivering it to different parts of the body. The mutation of this disease makes the cells become abnormal and irregular shaped. As a result, the abnormal…

Title- The Genetic Disease Sickle Cell Anemia Introduction- Throughout evolutionary history, advances in molecular biology allow molecular biologist to discover new genetic diseases. Sickle cell anemia is an inherited blood disorder in which there is a single amino acid substitution, which alters the structure and function of the hemoglobin. Although one might think that this disease only affects the circulatory system it actually affects many of the body’s systems, disrupting its functional…

While Sickle Cell Anemia is more common in certain ethnic groups, people should be aware of sickle cell. Sickle Cell Anemia affects 1 out of 13 people and is diagnosed at birth. People with this disease live a life struggling pain and uncertainty. On the 15th of November 1910, Dr. James Herrick made the first discovery of sickle cell disease. He encountered multiple patients complaining of similar symptoms of acute chest pain. Dr. Herrick received a blood film, a test used to look for…

Sickle Cell Anemia is a birth defect that is “a genetic blood disorder caused by the presence of an abnormal form of hemoglobin” according to MedicineNet.com. Sickle cell is common to people that have ancestry with Africans. Sickle cell affects about 100,000 Americans, one out of every 365 African American babies, and one out of every 16,300 hispanic babies. Older children and adults with sickle cell disease may experience a few complications, or have a pattern of ongoing problems that make…

about this disease, let us look at the history of sickle cell disease. One type of sickle cell disease is sickle cell anemia. Anemia means a few abnormal amounts of red blood cells. The name sickle cell anemia is first coined in 1910 by U.S. physician James Bryan Herrick. In one of his severe anemia cases, he found abnormal shaped red blood cells. He described them as sickle-shaped cells. By 1949, U.S. physical chemist Linus Pauling displayed that hemoglobin in people with sickle-cell disease…

Sickle Cell Anemia is a trait or disorder that is characterized by abnormal hemoglobin which causes red blood cells to become crescentic or sickle shaped, erythrocytes and by speeding up hemolysis, due to substitution of a single amino acid. Low oxygen tension causes polymerization of the abnormal beta chains which changes the shape of the red blood cells to the sickle form. Sickle cells are fragile and they break apart easily they die leaving you with a poor amount of red blood cells. The red…

Sickle Cell Disease Throughout the world, approximately 300 million individuals are heterozygous for a mutation in the β-globin gene, meaning they carry the sickle cell trait (Key, Connes, & Derebail, 2015). Of those 300 million individuals, 100,000 Americans are affected by sickle cell disease, making it the most common inherited blood disorder. Every single cell in our body needs oxygen to function efficiently, and the role of hemoglobin in red blood cells is to transport oxygen from the lungs…

Sickle cell anemia is an inherited form of anemia where an individual has either a lack of red blood cell or dysfunctional blood cell, resulting in a lack of oxygen and nutrients to the cells. Normally, a red blood cell would be round, flexible, and flat in the center to allow easy passage in the blood vessels. However, the individual with sickle cell anemia will have cells that are rigid, sticky, and shaped like a crescent or sickle which is where the name comes from. Because of its unique…