Sickle-cell disease

According to “Essentials of Pathophysiology” by Carol Porth, “sickle cell disease is an inherited disorder in which abnormal hemoglobin (hemoglobin S [HbS]) leads to chronic hemolytic anemia, pain, and organ failure”. The recessive gene is inherited and appears as the sickle cell trait if heterozygous or sickle cell disease if homozygous with two HbS genes. The amount of hemoglobin that is affected by the gene depends on if they are heterozygous or homozygous, and therefore affects the gravity…

Genetic Disease: SCD Sickle cell disease is caused by the abnormal change in the haemoglobin gene that slows the flow of blood which causes lack of oxygen to the tissues. Yolanda Smith defines haemoglobin as, “an essential cellular component of the red blood cells that play the role of transporting oxygen in the blood to the bodily tissues where it is required”. ("News-Medical.net", 2015). There are two types of haemoglobin there is HbA that is found in normal red blood cells and HbS one that…

The journal article first talks about Sickle Cell Disease (SCD) being steadily rising in Ireland more than ten years. SCD raised because of immigration. This disease is most common in men. The condition of SCD makes the abnormal red blood cells not function properly. The life span of a person with SCD is shortened. This disease is a global health problem.There was a non - funded neonatal screening program for all the children identified SCD in Republic of Ireland born after 2005. The screening…

Sickle Cell Disease (SCD) is an inherited blood disorder, in which people have abnormal hemoglobin. This causes a variety of problems for the person throughout their entire life, but severity of the disease varies. Sickle Cell Disease is not necessarily deadly, but it decreases the average life expectancy of a persson. In countries like the United states, a person with Sickle Cell Disease has a life expectancy of about forty to sixty years. Other than stem cell transplants there is no cure…

blood transfusions and bone marrow transplants. Many people are blessed never to have to worry about those things their entire lives, but that life is a reality for a person with sickle cell disease. Some compare sickle cell to cancer, but they are very different. Similarly both have severe effects on the body from the diseases themselves and from the strenuous treatment procedures. Through all the hardships sufferers, have to have hope and never give up. Arnold Schwarzenegger once said,…

Name of disease Sickle Cell Disease Location 11p15.4 – chromosome 11, on short arm of chromosome, region 1, band 5, sub-band 4 Gene/locus HBB – haemoglobin subunit beta HTML reference Stumpf, A.M. (2013). Sickle cell disease Available form: http://www.omim.org/entry/603903?search=Sickle%20Cell%20Disease&highlight=cell%20sickle%20disease Frequency More than 230 000 children with sickle cell disease are born in Africa every year, which makes about 80% of the global total. In Europe estimated…

and consists of many diseases that can kill you if not cured, if they have a cure , or treated properly…

The Crescent Moon Disease: Sickle Cell Sickle cell anemia is a disease that is passed throughout families. Sickle cell affects the red blood cells, which cause the blood cells to look like a crescent moon instead of looking like a disc, like the photo included above. There are two types of Sickle cell: Sickle Cell Anemia and Sickle Cell- Hemoglobin C. Sickle Cell Anemia is the less severe one out of the two. Sickle Cell Anemia affects many racial and ethnic groups. One in four hundred…

Sickle cell disease is a major health burden in the Indian community. It contributes to millions of deaths worldwide however it is most prevalent in tribal populations in the rural sectors of India. “Sickle cell disease or SCD is an inherited abnormality of the red blood cell characterized by chronic haemolytic anemia with numerous clinical consequences” (Ugwu 87). The shape of hemoglobin, which gives red blood cells their color is turned from an oval to a crescent shape when the sickle cell…

Sickle Cell Disease There are many different types of hereditary diseases that affect people’s lives every day. One of them being sickle cell disease. Sickle cell disease or sickle cell anemia “is the result of abnormal hemoglobin” (Bloom 3). Hemoglobin is the “oxygen-carrying molecule of the red blood cell” (Bloom 3). In sickle cell disease, the red blood cells take shape of a crescent moon, leading to lifelong health problems. Sickle cell disease is an obstacle for thousands of people’s lives…