Sickle-cell disease

Sickle Cell Anemia Sickle cell anemia is an inherited disorder that allows for some treatment, however the average life expectancy of a patient will Sickle cell anemia is only 30 years. An inherited gene causes the hemoglobin in the blood to become misshaped. Hemoglobin is the part of the red blood cells (RBC) that carries the oxygen to all of the body’s tissues and organs. This leads to inadequate amounts of oxygen to be carried on the hemoglobin, thus resulting in insufficient oxygenation for…

Sickle cell anemia is an inherited disease. It occurs due to the change of single nucleotide in the beta globin chain. In this disease, normal red blood cells get changed into to sickle shaped or disc shaped showing concave from the center. They may change their shape in the form of banana. Cause of disease: Sickle cell anemia is caused due to deficiency of iron in the body which results in change in the shape of red blood cells. How it occurs: Red blood cells are flexible due to which they…

Living With Sickle Cell Anemia Chasta D. Jones Text College Living With Sickle Cell Anemia Sickle cell anemia is a condition where there is not enough healthy red blood cells to carry enough oxygen within a persons body. The red blood cells become rigid, sticky, and shaped like crescent moons or sickles. The cells irregular shapes can get stuck in the blood vessels causing blockage of blood flow though the body. The sickle cells become weak and break apart and die. This leaves…

Sickle Cell Anemia or also known as Sickle Cell Disease, is a severe hereditary form of anemia in which a mutated form of hemoglobin distorts the red blood cells into a crescent shape at low oxygen levels. When these red blood cells are affected in this way, the irregular shaped cells can get stuck in small blood vessels. If this happens, it can slow or block blood flow and oxygen to parts of the body. Symptoms of this disease easily affect people’s way of life, comfort, and overall…

Aminata’s child will have sickle cell anemia is a 1 in 20 chance. By calculating the probability that Nelson is a heterozygous carrier of the HbS gene (.67), then the probability that Aminata is also a heterozygous carrier of the HbS gene (0.30), and finally the probability that two heterozygous carrier parents will produce heterozygous recessive offspring with sickle cell anemia (0.25), I calculated the probability of Nelson and Aminata having a child with sickle cell anemia. When all three of…

The human body is made up of trillions upon trillions of cells. Each cell has a nucleus, inside that nucleus are chromosomes. Each chromosome is made up of miniscule deoxyribonucleic acid (DNA) strands. Segments of that DNA code for hair color, eye color, height, body type, etc. In some cases, genes will mutate, thereby modifying the DNA code and resulting in a genetic disorder. A mutated gene can either be inherited or acquired in one’s lifetime. Genetic disorders are obtained one of two…

Sickle cell crisis is an acute condition of sickle cell anemia. Sickle cell anemia is a genetic condition. Both parents must be carriers of the gene in order for a baby to be born with sickle cell anemia. In the United States, the gene predominantly affects black people of African decent. Sickle cell anemia is a disease where there is an inadequate number of healthy red blood cell throughout the body. A blood test can check for hemoglobin S — the defective form of hemoglobin that underlies…

Gene Therapy in Hemoglobinopathy Hemoglobinonpathy is the lack of a molecule or total blood hemoglobin chains. Hemoglobin is found in red blood cells. Example of the disease is alpha-thalassemia. This happens due to lack of one or two series of alpha-Zhlobin or beta (where the shortfall in one or two Zhlobin beta), for example, inheritance thalassemia is inherited through a recessive trait autosomal recessive physical. There are differences between the alpha thalassemia and beta…

Inherited red blood cell disorders are grouped together and called Sickle Cell Disease (SCD). Among these disorders, the most severe is Sickle Cell Anemia (HbSS). This red blood cell disorder is inherited and affects the RBC’s ability to carry oxygen (Addis, 2010). Normal red blood cells are disc shaped, but in sickle cell anemia the cells are shaped differently. Red blood cells in clients with Sickle Cell Anemia are sickle-shaped, crescent shaped (Allen & Harper, 2014). These abnormally…

Sickle cell disease is an inherited disorder that is caused by a mutation in the DNA sequences that codes for the beta chain of the hemoglobin protein. Red blood cells are, normally, flexible and round, but with the sickle cell anemia the red blood cells become sticky, rigid, and crescent shaped. The Hemoglobin protein carries oxygen in the red blood cells throughout the body. With the disease, the blood cell’s shape can cause them to get lodged in the blood vessels resulting in the obstruction…