Serum albumin

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  • Bovine Serum Albumin

    Introduction Bovine serum albumin (BSA) is a transport protein in cow’s blood stream, similar to Human serum albumin in human blood. It binds different types of drugs for delivery to various parts of the body. One of these drugs is warfarin, a blood anticoagulant. This research project’s focus was on the interaction between BSA and warfarin derivatives; our assumption was that the protein binding site has different affinities for different warfarin derivatives; this was to be determined by comparing the equilibrium constants (Keq) and the Gibbs’ free energies of a number of warfarin derivatives. To study this, four warfarin derivatives were used, namely racemate mixtures of 2’-Fluoro warfarin (2’FW), 3’-Fluoro warfarin (3’FW), (R)-4’-Fluorowarfarin,…

    Words: 894 - Pages: 4
  • Human Serum Albumin Summary

    Summary Human Serum albumin (HSA) is a plasma protein in charge of the transportation of the fatty acids (Bhattacharya, Grune & Curry, 2000, p.721). HSA promotes the transportation capacity of plasma because it is currently at around 0.6Mm enabling it to carry more than six molecules of fatty acid. In addition, the HSA binds and agitates the pharmacokinetics of various drugs compounds. The HSA-fatty acid has two drug-binding sites, which are the sub-domains IIA and IIIA. The fatty acid IIIA…

    Words: 842 - Pages: 4
  • Efficacy Of P. Putida And P. Fluorescens Isolates

    samples were randomly collected 0, 3rd and 6th days after drought stress (DAS) with five biological replicates for each treatment group. Plant height (cm) was measured from the base of the plants to the tip of longest leaf. Root and shoot fresh weight (g) and lengths (cm) were measured from respective plants on each day of sampling. For dry weights of roots and shoots, the samples were dried at 72 ºC for 72 h. Samples for RNA extraction, cDNA synthesis and qRT-PCR were immediately frozen at −80…

    Words: 1009 - Pages: 5
  • Bovine Serum Albumin Case Study

    Bovine serum albumin (BSA) is usually used for generation of nanoparticles (NPs) in drug delivery systems. This paper presents a study on the simple coacervation method for fabrication of BSA nanoparticles.An artificial neural network (ANN) model was developed to predict the diameter of nanoparticles based on experimental data. Effect of pH, temperature, initial BSA and cross linker concentration, molar ratio of BSA to ethanol, agitation rate and rate of ethanol addition were investigated on the…

    Words: 951 - Pages: 4
  • Elder Mistreatment Case Study: Overview In His Home

    In section I (General Assessment) I found that the clothing aspect was not mentioned however we might assume that since the sheets were dirty and the patient was soiled on each visit, then this could be rated as having poor hygiene. His nutrition status was somewhat difficult to determine as a weight was not provided due to the patient not being able to get on a scale. However, his blood work was taken on the prior visit and his albumin level was 2.8 on a scale of 3.4-5.4 g/dL and his pre…

    Words: 1431 - Pages: 6
  • Ckd Research Paper

    List A: Microbiology of Inflammatory COPD Exacerbation Microbiology Results Indication Sodium Level 142 mmol/L Normal Potassium Level 5.1 mmol/L Normal Chloride Level 101 mmol/L Normal Bicarbonate Level 29 mmol/L Normal Urea Level 7.3 mmol/L High (2.9–7.1 mmol/L) Creatinine 91 umol/L Normal eGFR CKD-EPI 73 mL/min/1.73m^2 Normal Bilirubin Total 10 umol/L Normal Protein Total Level 68 g/L Normal Albumin Level 28 g/L Low (35–55 g/L) ALP 68 U/L Normal GGT 16 U/L Normal ALT 29 U/L Normal AST 22…

    Words: 1253 - Pages: 6
  • Gel Filtration Chromatography Lab Report

    Observe Ligand-Protein Interaction using Gel Filtration Chromatography (Phenol Red Binding to Bovine Serum Albumin) Introduction: Serum albumin is often known as blood albumin, and is the most abundant protein in humans and other animal plasma. Serum albumin is also known as a carrier protein by non-specifically binding several biomolecules. It is essential for maintaining the osmotic pressure that is needed for body fluids distribution between body tissues and intravascular compartments.…

    Words: 910 - Pages: 4
  • Measurement Of Albumin Essay

    3. Measurement of glycated albumin As mentioned before, the measured albumin is considered a reliable tool to supplement other methods of measuring blood glucose, such as HbA1c and standard assays for glycemic control and diagnosis diabetes [30]. The HbA1c lifespan is estimated to be about 90 to 120 days. Thus, it is known as an indicator for the assessment of long-term glycemic control [17, 31]. However, the level of HbA1c is not suitable for the assessment of the patient’s status in some…

    Words: 1689 - Pages: 7
  • Bioanalysis In Biopharmacenology

    LBAs use highly specific antibody based interations and can detect a unique epitope on a protein of interest at a high sensitivity. However, the dynamic range of this technique is just 10^2. LBAs can detect both, active and free forms of a large molecule drug in samples. Aside from this aspect, they take a long development time of months and have low specificity may be because of its antibody cross reactivity. With all these limitations of LBAs, they can not detect diverse proteins and peptides…

    Words: 1888 - Pages: 8
  • Western Blot Technique Essay

    13. What is the process resulting in antigen and antibody moving toward each other? One dimensional diffusion Enzyme-Linked Immunosorbent Assay 14. In the “sandwich” analogy of the direct ELISA, what is the “bread”? Antibodies What is the filling? Antigens 15. Describe some advantages of using the ELISA technique to process a large number of samples. The advantage of Sandwich ELISA is that the sample does not have to be purified before analysis,…

    Words: 834 - Pages: 4
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