cholesterol and take advantage of the clustering of receptors there.1 Attachment to the lipid membrane is advantageous to the virus as endocytosis uses (PI)-3 kinase…
Noroviruses are non-enveloped, single-stranded, positive sense RNA viruses that cause acute gastroenteritis in humans (1-4). Noroviruses have been referred to as ‘cruise ship viruses’ from well-publicized cruise ship outbreaks although these outbreaks account for less than 1% of all outbreaks worldwide (5). The symptoms and illness associated with Norovirus infections is often referred to as ‘stomach flu’, despite little resemblance to the influenza virus. Noroviruses are responsible for 21…
with (xl3). prbp3: third dsRBD of protamine binding protein, trbp3: third dsRBD of TAR-RNA binding protein, Dros: a dsRBD from a Drosophila protein of unknown function. DMStau, a type B dsRBD from Drosophila Staufen protein 4.4. Different activities between Xlrbpa and PACT In this work we could show that Xlrbpa inhibits human PKR in Saccharomyces cerevisiae cells and that this inhibition is due to the RNA binding-ability of Xlrbpa. Others have cloned the human homologue of Xlrbpa, PACT from…
is usually caused by the virus HSV-1, or herpes simplex type 1, but can also be caused by HSV-2. In a previous study, it was found that 67.6% of Americans possessed antibodies for HSV-1, establishing HSV-1 as an exceptionally prevalent virus even in developed countries 9. The virus is spread through skin to skin contact between an individual exhibiting viral shedding, and an unaffected person, but can also be contracted through exposure to surfaces that contain the virus. Once HSV-1 is…
According to scientists the conventional wisdom of viruses says that about viruses, scientists say that viruses aren’t bigger than bacteria and that the majority have viruses have 10 or less genes. But organisms such as the meme virus, mega virus and the Pandora virus prove us wrong. In some cases, some of these controversies to the change of biological evolution is in heredity by accident, natural in nature or caused by mutation. Before 2003 there only two kinds of living things on earth which…
Neuroblastoma and microRNA- 34a is commonly mentioned together in many articles and studies around the world. With the advance in medicine and new discoveries, there has been found a dependence relation of neuroblastoma with these specific type of microRNA since it has been discovered how it could eliminate cancer eternally. MicroRNA-34a has not only revolutionized scientists but the world in general because of its ability to destroy neuroblastoma but also because is a new natural genetic…
to the Principles of Virology Danielle Morency SOCI 241-01 Chapter two of Viruses, Plagues, and History focuses on viruses. Viruses have an incredibly simple design; they are made up of a small amount of genetic material, either DNA or RNA, in a coat of protein molecules. Viruses are obligate parasites, meaning that they depend on the life of others, including plants, animals, bacteria, fungi, and protozoa, to replicate meaning they cannot multiply until they invade a living cell.…
viruses [2, 5]. About half of these children did not have any known medical conditions. Therefore, IB may contribute to a higher attack rate among children and adolescents, than among adults, and infections may be more severe [1, 4, 5]. An influenza virus infection typically presents as general malaise with fever, headache, cough, rhinorrhea; most cases manifest as a mild upper respiratory infection or a primary viral pneumonia/pneumonitis. Clinically, infections by the influenza viruses or…
Roberts and colleagues were investigating how this virus was able to spread to neighboring cells (Roberts et al., 2014). While conducting their research, they figured out that the influenza A virus used an alternative pathway to infect cells through the use of GFP (Roberts et al., 2014). The GFP-tagged influenza A virus gave the researchers a visual of how the viral proteins moved from cell to cell in one direction through intracellular…
Measles and Krippin virus stem from the same family but are radically different. Both viruses have a (-)ssRNA genome, as KV is developed from MV. Due to the common origin, there are similarities, however, one of which being developing a cancer treatment for each virus. In KV, the measles virus was genetically modified to target and kill cancer cells. As Alice Krippin states, in 10,009 clinical trials, there were 10,009 cancer-free patients (Lawrence). In Measles, the virus targets cells…