RNA virus

Epidermodysplasia Verruciformis, an autosomal recessive inherited skin disorder characterised by eruptions of wart-like lesions that may occur anywhere on the body. These lesions are caused by infection with the human papillomavirus or HPV. The reason Epidermodysplasia Verruciformis is also called the Tree-Man Disease is because the wart like lesions in and on the skin have a bark like texture and appearance. The Tree-Man Disease is not contagious, because it is genetic, it can’t be spread by…

Angel man syndrome is a very unique syndrome. This is a lifetime, short time, syndrome. People with angelman syndrome have issues with balance, movement, seizures, speech impairment, very small head size and sleep. Also kids or adults who are diagnosied with this syndrome, they are all very happy, they laugh a lot, also they all have big bright smiles. The most major cause of this disease is a gene that is missing. A gene called ube3a which is a gene that focuses on targeting proteins. Four…

Gene therapy is an experimental form of treatment that modify the expression of an individual’s genes or correct abnormal genes by replacing a faulty disease-causing gene with a working version, or by introducing a new gene to cure a condition or modify its effects. For example, diseases such as cystic fibrosis, muscular dystrophy, hemophilia, and many cancers result from the presence of defective genes. Gene transfer first appeared in 1960s. The first therapeutic use of gene transfer was…

Bacteriophages (phages) are viruses that exclusively infect and replicate within bacterial cells. Phages are ubiquitous, with an estimated 1x106 particles per drop of seawater and as many as 1x108 particles per g of soil. Phage predation destroys an estimated one-half of the bacterial population worldwide every 48 h, hence regulating the population dynamics of natural bacteria (Deresinski 2008). Bacteriophages attach to their host cell by specialized structures called tail fibers, inject their…

Regan Hansen – A006569939 Biology 3300 - 503 Library Unknown – Neisseria Gonorrhoeae The characteristics that I had to look for was a gram negative coccus, often in flattened pairs, non-motile, aerobic, acid from glucose but not maltose, nitrites not reduced, and isolated from a sick human. I found out that there seems to be a very small amount of gram negative coccus bacteria. The biggest factor that helped me in determining my unknown was seeing that the acid came from glucose and not…

HSV-1 and HSV-2 replication is reduced in rhesus macaque fibroblasts: The aim behind this experiment was to check whether rhesus monkey cells are more effective against the HSV-1 and HSV-2 replication than Human TRIM5. Rhesus Macaque fibroblast cell lines and HeLa cell lines were infected with HSV-1 KOS and HSV-2 186 syn+ strains at MOI=3 PFU/cell and harvested at different time points post infection. The viral load at these time points are shown the Figure 1. From the figure we understand…

This condition is caused by a virus. The virus is spread in droplets that are sprayed when a contagious person talks, sneezes, or coughs. A person with rubella is contagious from about 1 week before the rash appears until about 1 week after it goes away. What increases the risk? This condition is more likely to occur in children between the ages of 5 and 15 years old. What are the signs or symptoms? Symptoms usually appear 2–3 weeks after your child is exposed to the virus. The most common…

Differential diagnoses for a patient that presents with a history of living in a communal-type holding center for the past week, an itchy, pinpoint, papular rash on the extremities can be scabies, insect bites, atopic dermatitis, contact dermatitis, and pityriasis rosea. Due to the fact that the child has been living in a communal-type holding center, there is no telling what insects the child may or may not have been around. An insect bite can present with symptoms of erythema, local pain,…

Rabies is caused by a virus of the same name that is shaped like a bullet; it is oblong on one end and flat or concave on the other. The the surface of the virus, expect the flat end, is covered in knobs of glycoprotein. The rabies virus is most commonly transmitted through the saliva of an infected animal. Though transmission has occurred through transplantation, this occurrences are extremely rare and the virus and subsequent disease are overwhelmingly transmitted by any warm blooded animal.…

Gene therapy is where normal genes/ genetic material are inserted into the cell where missing or malfunctioning genes are, potentially correcting any disorders caused by the faulty gene. Leading research of gene therapy to treat Cystic Fibrosis has made ground breaking discoveries in ways in which faulty or missing CFTR genes (responsible for moving salt and water out of cells) can be replaced via Vectors, to ensure the protein can regain its normal function. This annotated bibliography provides…