RNA polymerase

There are millions of genes that are present in the human body. For the most part, genes are responsible for pairing DNA bases with the correct base, and directing the production of RNA molecules, which synthesizes proteins and regulates the expression of other genes, but when some genes are altered or manipulated during DNA replication, they can be very dangerous for the body, and can be possibly deadly. Some of the genes in our body that are mutated can play a positive role in the body in ways…

CDV is an enveloped, non-segmented, single-stranded RNA virus and is a member of the Morbilliviruses, thus closely related to measles virus (LAMBandKOLAKOFSKY 2001; VANDEVELDE and ZURBRIGGEN 2005). CDV possesses a nucleocapsid containing the viral genome, which consists of the nucleoprotein (N) and the polymerase complex including the (P) and (L) proteins (DEMETER et al., 2007). The membrane protein (M) is located at the inner surface of the envelope, which exhibits two surface glycoproteins:…

Lymphocytic Choriomeningitis virus (LCMV) belongs to the Old World arenavirus family of enveloped viruses (Buchmeier et al., 2007). LCMV in particular has served as model organism from many significant studies in the field of immunology such as the Nobel Prize winning study of the Major Histocompatibility Complex (MHC) by Zinkernagel and Doherty (1975). LCMV’s natural reservoirs are the common household rodents (Traub, 1936). Household mice have shown to attain persistent asymptomatic LCMV…

with the ATG codon. Most biological activities are carried out by proteins. In order to have the DNA sequence that reads ATG-ACT-CAT-GAG-TGA to be translated into the RNA to build a protein there has to be proteins that are not the same to be able to perform this function. The DNA also needs to be changed into the RNA and the RNA has to be changed into a protein. In order for the cell to have a proper function the proteins that are necessary need to at the time that is proper be synthesized.…

1. Where and when was the first case of Zika virus infection reported? (10 pts) In 1947 Zika virus was first isolated from a monkey coming from the Zika forest in Uganda1. In 1952 first human infections were reported in Uganda and the United Republic of Tanzania1. Reference [1] The History of Zika Virus." World Health Organization. World Health Organization, n.d. Web. 02 Dec. 2016. 2. What are the common symptoms of Zika virus infection (Zika virus disease)? (10 pts) When a person is infected…

research: Aims and Objectives: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development Aim2: To characterise rDNA chromatin organisation in the oocyte Aim3: To elucidate the transcriptional machinery of RNA Polymerase I in the oocyte Experimental Approach: Aim1: To address the roles of the Hira complex in rRNA transcription and embryonic development The Hira histone chaperone complex is an evolutionarily conserved complex, which is composed of Hira, Ubn1…

dogma of molecular biology? The central dogma is the explanation of how genetic information flows as it is passed from DNA to RNA to protein. DNA replicates and converts the information it carries into RNA, this process is called transcription. During transcription the information is passed through nucleic acids and there is no need for a change in the “language.” When RNA continues the flow of information and it is passed to proteins, this is called translation. It is called translation…

Transcription is a process which information from DNA is converted into its RNA equivalent which also refers to the synthesis of RNA copy of information encoded on DNA. The same principles of transcriptional regulation apply to both eukaryotes and prokaryotes. Transcription involves in access of transcription apparatus to DNA, recognition of promoter sequences, initiation of RNA synthesis, elongation of RNA, and termination. Transcriptional in eukaryotes is more complex compared to prokaryotes…

A human being and a chimpanzee are quite similar not because of physical features but because of the DNA, they inherit and what makes these species so unique to one another. All living cells contain DNA, which is the basic unit for growing, reproducing, and surviving. DNA, Deoxyribose Nucleic Acid is comprised of 4 different types of bases; adenine, thymine, guanine, and cytosine that are proteins. These 4 bases rely on each other because of adenine pairs up with thymine, while cytosine…

in bacteria, transcription officially begins when an RNA polymerase and a sigma subunit bind at two different sites at a promoter. An open promoter complex is formed when DNA unwinds in this area and RNA synthesis starts because of a holenzyme. This is where regulation really comes into play, because transcription will continue as long as it has enough of what it needs until it hits a termination sequence. After which, the brand new produced RNA and enzyme are let go from the template. Until…