RNA interference

majority of enzymes are fibrous proteins. d. The majority of enzymes are globular proteins. ANS: D PTS: 1 TOP: 23.1 - WHAT ARE ENZYMES? 2. In addition to proteins, which type of molecules sometimes function as enzymes? a. carbohydrates c. lipids b. DNA d. RNA ANS: D PTS: 1 TOP: 23.1 - WHAT ARE ENZYMES? 3. Which of the following is true of enzymes? a. They shift the position of a chemical equilibrium. b. They speed up the rate of a chemical reaction. c. both a and b d. neither a nor b ANS: B PTS:…

WHO FIRST DISCOVERED MITOSIS? Mitosis was first discovered in the early 1880s by Walter Flemming. Walter Fleeming was a German biologist. He developed most of his study on cells and the chromosomes that are inside of cells. In 1878, the claimed that cell duplicate in the process called mitosis. Flemming died on August 4th, 1905. HOW DID MITOSIS GET IT NAME? "Mito-" which mean "thread" in Greek. The process of cell division are described as threads because during the process of…

DATABASES 1. Assembly Assembly database is needed to provide a systematic organization of genome. To accomplish that, the genome is fragmented into small pieces and is sequenced for many times to try to recreate the set of chromosome sequences. This database provides a unique tracker in form of accession so that users can identify changes to an assembly in precise locations whenever needed. There are two different types of assembly updates which are major release and minor release. 2.…

G-protein coupled receptors are found in eukaryotes, and are encoded by around 1-3% of the genes in the genome. In this essay I will discuss the general structure and model of activation of GPCRs, as well as how this model has been realised, through the study of bacteriorhodopsin, a homology model of GPCRs. There are many examples of GPCRs illustrating how GPCRs can have a wide range of cellular consequences and I will discuss how the activation of rhodopsin, sphingosine-1-phosphate receptors,…

CRISPR is a technique that made genomic editing significantly easier. CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated protein) is a RNA-guided nuclease for precise genome editing in diverse organisms. In 1987, when scientists were studying the bacteria's immune system, they discovered a pattern of short, repeating, palindromic DNA sequences separated by short, non-repeating, "spacer" DNA sequences (Figure 1). How CRISPR/Cas works in bacteria: As…

BigDye® Terminator v3.1 Cycle Sequencing Kit provides everything we need in order to generate a sequence all we need to do is add one primer and the DNA template. These reagents are suitable for performing fluorescence-based cycle sequencing reactions on single-stranded or double-stranded DNA templates, on polymerase chain reaction (PCR) fragments, and on large templates. First, you must prepare your template by performing a DNA extraction and purifying your template. The purification will be…

the gene to the protein product. This process is how DNA is coded for RNA, which basically is the turn code for the proteins in our body. DNA is in every living thing, which is the molecule that carries genetic material from the parents to their offspring. Basically, it is the most important thing in the human structure of the body. For it carries the necessary information that is needed for the construction of proteins and RNA. There is always decoding going on in the body which is using the…

Replication Inhibitors Replication inhibitors interfere with DNA synthesis. There are many of these inhibitors, but they typically work via two main mechanisms. One of these mechanisms involves either disrupting molecules that are needed for DNA polymerization or those needed in order to initiate replication. The other mechanism is by interfering with replication checkpoints that are involved in regulating the replication process. These checkpoints sometimes do this by triggering certain…

Rhiju Das came to Butler on March 21st to give a lecture on how a videogame has helped code for RNA. Diseases can be traced back to RNA molecule folds. RNA vaccines have a design problem because it is hard to tell what sequence is correct. NUPACK 08 was the most sophisticated computer system and it got the sequence wrong. However, Taipan was designed by a videogamer and it had the correct sequence. Therefore, Das designed a game called Foldit in which players solved puzzles of computers. A…

their DNA2. Prokaryotic DNA replication occurs in the cytoplasm and there’s a single origin of replication3. DNA polymerase III carries out both the initiation and elongation mechanisms, DNA polymerase I carries out DNA repair, gap fillings and removes RNA primers and, DNA gyrase is needed to relieve the strain when DNA is being unwound3. In prokaryotic DNA replication, Okazaki fragments are large, about 1000-2000 nucleotide long and the replication process is very rapid occurring at a rate of…