RNA interference

in order to correct genetic disorders. Gene therapy uses a vector, typically a virus to deliver a gene to the cells where it's needed. Once it's inside, the cell's gene reading machinery uses the information in the gene to build RNA and protein molecules. The proteins, RNA can then carry out their job in the cells. Gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder by inserting a gene into a…

proteins are the workhorse of the cell, as they make up most tissues and organs of the body. Lipids are the storage areas. They contain the extra energy that the organism does not currently need. Nucleic acids are the parts of cells that include DNA and RNA, which dictate cell replication, and specialization. Every single organic molecule, from carbohydrates to nucleic acids is just as important as the other. All of the molecules play significant roles in allowing the organism to function…

All genes of living organisms are translated into proteins according to a single genetic code. Eighteen out of the twenty amino acids are encoded by multiple codons, called synonymous codons. If the ultimate goal of protein translation is to produce the encoded amino acid, each synonymous codon should be used equally. Interestingly however, biased usage among synonymous codons occurs in organisms like Escherichia coli and yeast. Codon usage bias refers to the fact that some synonymous codons are…

et Assignment 1.2 DNA or deoxyribonucleic acid is a molecule which carry genetic instruction used in the functioning ,development ,reproduction and growth of all living organism including viruses. DNA are composed of simpler monomer units called nucleotide. They are termed polynucleotide as DNA have two strands. Nucleotides is composed of four nitrogenous base, they are ADENINE(A), THYMINE (T),CYTOSINE(C), and GUANINE (G).””(DNA) DNA bases pair up with each other, A:T and C:G, to form…

1. Where and when was the first case of Zika virus infection reported? (10 pts) In 1947 Zika virus was first isolated from a monkey coming from the Zika forest in Uganda1. In 1952 first human infections were reported in Uganda and the United Republic of Tanzania1. Reference [1] The History of Zika Virus." World Health Organization. World Health Organization, n.d. Web. 02 Dec. 2016. 2. What are the common symptoms of Zika virus infection (Zika virus disease)? (10 pts) When a person is infected…

Epigenetics is the modification of the genome to regulate gene expression. This process is achieved through a variety of different mechanisms including but not limited to, chromatin condensation, acetylation modification, and methylation modification. Gene expression can also be altered through a number of non-epigenetic mechanisms, such as environmental factors, like temperature, and the introduction of endocrine disrupting chemicals (EDC) into the environment. The level of chromatin…

percent of cancers were due to random mistakes, 29 percent were due to environmental factors or people’s lifestyles, and 5 percent (5%) due to inherited mutations [2] The transcription of a gene begins with transcription elements, mostly protein and RNAs, binding to regulatory sites on DNA. The frequency of this binding affects the level of expression. Experiments have verified that a stronger binding site will increase the effect of a protein on transcription rate. On the other hand, since the…

Figure 5. Rosiglitazone (highlighted in green) forms three salt bridges with neighboring atoms at the hydrophilic end of the LBD. Rosiglitazone binding to PPARγ causes a conformational change within the complex that causes the dissociation of the endogenous ligand and the recruitment of a nuclear receptor coactivator 2, NCoA-2. This similarly occurs in the other half of the complex: RXRα Receptor A type II nuclear receptor as well, RXR-α heterodimerizes with PPARγ. The ligand that…

1) The major difference between these two is that the RNA viruses have RNA in their genome while the DNA viruses have DNA in their genome. Both the DNA and RNA cannot be found in the same virus. RNA virus first adsorbs to the host cell surface. Then the attached virus fuses with the endosome membrane. Unlike RNA viruses, DNA viruses pass their DNA into the nucleus of the host cell and not into the cytoplasm of the host cell. 2) Lysis: refers to the breaking down of the membrane of a cell, often…

Journal Article Assignment Name: Elaine Lieu ID: 20624252 Section: 112 TA: Jocelyn Chan Cell Bio Bites Topic: Ribosomal Function and Ricin – Why is this product of castor beans so lethal? Define the key terms (scientific words) in your own words. (notes or textbook can be used as sources) Ricin toxin A (RTA) → toxic protein from seeds of castor plants. Subunit A depurinates adenine in cells Mutants → The process of a gene or chromosome being altered Apoptosis → cell suicide Cell signaling…