1- Introduction Benzosuberone based compounds are important classes of biologically active compounds that attracted a great deal of interest in the medicinal chemistry due to their potent biological activities and wide range of pharmaceutical applications [1-6]. Several publications recorded that some of benzosuberone derivatives possess antipyretic, anti-inflammatory, antimicrobial, antiulcer and antitumor activities [1-6]. As an indication for the importance of the benzosuberone based…
Topical Nerve Growth Factor (NGF) Application In an animal model the topical application of NGF to wounds and ulcers leads to a statistically significant decrease in the wound perimeter (66%) vs. controls.[8, 23, 77, 120] Clinically, topical application of NGF leads to the repair of neurotrophic corneal ulcers, recovery of corneal surface sensitivity [36, 119] and diabetic foot ulcers.[73] Basic Fibroblast Growth Factor (bFGF) Topical application of bFGF enhances the healing for operative…
This is produced in the liver; these hormones lead to Blood Sugar Imbalance and Diabetes, Weight Gain and Obesity, Immune System Suppression and many more problems within the body. 3. Psychological effects of stress Psychological effects of stress are the effects that have to do with mental health and the way in which the mind can cope under the pressure. • Chemical imbalances:…
in power lines is acceptable in relatively short cables (approximately up to 200–300m), but is very bad in longer cables [31]. Hence, longer PLC networks are expected to be equipped with the repeater technique. Noise is another major problem on the system. The impedance of a power supply network is time variant, because electric devices are randomly connected to the grid. Noise in the electric distribution network is caused by many electric devices, such as halogen lamps, microwave ovens, and…
of human and system operation of job. It employs 21,000 based in the US while 22,0001outside the US. Identifying relational databases, as a great business opportunity is one of several brilliant moves Ellison made over his career. Larry…
Modern spaceflight is something that is wondrous to many people. It is an important topic mainly because advancements made in this field could determine the future of the planet and the human race. The main question on this topic is who should be leading the effort to explore the cosmos, private persons and companies or governmental institutions? Although the modern day space initiative is being mostly spearheaded by private persons and industries, in my opinion, government funded space programs…
entire globe. Additionally, due to its constant changing it is very easy for an animal influenza to change into a human effecting one (“Influenza” (Flu)). Therefore, it is very difficult to treat. An influenza virus is one that attacks the respiratory system which results an individuals coughing and sneezing. Additionally,…
Dell successfully carried out a very innovative business model at the time, especially in the consumer PC industry. When thinking about electronics, there is usually a clear distinction between the company that assembles the devices and the company that resells them for profit. This is usually the case when the manufacturing company does not have the expertise to manage the distribution channels required for efficiently reaching customers. Dell watched closely this model for years and identified…
‘Viennese economist Otto Neurath developed the concept of a command economy to control the hyperinflation after World War I.’ At first look, a command economy appears to be the less developed system and indeed does not function as productively as a market economy does. ‘Command economies are unable to efficiently allocate goods because of the knowledge problem, or the planner’s inability to discern how much of a good should be produced. Shortages…
Abstract Objectives: The anticonvulsant effect of cannabinoid compound illustrated in various models of seizure and epilepsy. On the other hand, there are controversial findings about the role of large conductance calcium-activated potassium (BK) channels in the pathogenesis of epilepsy. Also, there is no data regarding the effect of co-administration of cannabinoid type 1 (CB1) receptor agonists and BK channels antagonists in the acute models of seizure in mice. In this study, the effects of…