Replication

An “Innovation vs. Replication” report compared the financial performance of 500 firms varying in size and found that small businesses with business models centred on low levels of replication and high innovation, showed more growth than models with high levels of replication. Additionally, they also found that large businesses with only high levels of innovation and low levels of replication had a lower average financial position (Aspara 2009). This reflects…

large-scale urban environment. In a similar manner, the Louvre presents large rooms with Egyptian columns and statuary that also depict the replication of Egyptians historical sites within the confines of the museum. This contemporary placement of Egyptian artifacts presents architectural amalgamations in the museum for the visitor to observe as a replication…

long and single stranded coding region is bracketed by short palindromic terminal sequences capable of folding into hair pin duplex. The parvovirus replication begins with attachment and genome enters in a host cell, replication occurs in the nucleus. Their DNA must be a replicon. Parvovirus replicate their DNA through a sequence of duplex. For replication 3’ end serves as a primer due to the looping hairpin structure, helicase opens up 5’ end for polymerase activity. Concatermeric genomes are…

HSV-1 and HSV-2 replication is reduced in rhesus macaque fibroblasts: The aim behind this experiment was to check whether rhesus monkey cells are more effective against the HSV-1 and HSV-2 replication than Human TRIM5. Rhesus Macaque fibroblast cell lines and HeLa cell lines were infected with HSV-1 KOS and HSV-2 186 syn+ strains at MOI=3 PFU/cell and harvested at different time points post infection. The viral load at these time points are shown the Figure 1. From the figure we understand…

its efficiency and capabilities. For example, eukaryotic DNA polymerase requires a short RNA primer to begin replication on the lagging strand, because of this replication cannot continue replication all the way to the end of the chromosome, and it has been shown that anywhere between 50 and 150 base pairs are lost from the ends of eukaryotic chromosomes for each round of DNA replication (Kim, et al. 2016). This is problematic, because…

and microarrays led to a new way for sequencing genes : the Next Generation Sequencing (NGS). How do Sanger technique and NGS work ? What are their applications? Sanger sequencing The Sanger technique is based on the replication of DNA. The unknown sequence is inserted in a replication plasmid then it is cloned by E. coli (Escherichia…

expression of approximately 25% of the 553 cell cycle-regulated genes in the genome (Reisenaur et al., 1999). This protein also blocks initiation of DNA replication by binding to five sites within the chromosomal origin (Brilli et al.,2010). During the G1 phase when C. crescentus transitions from swarmer cells to stalked cells, ctrA suppresses replication in the swarmer…

This paper is going to describe the replication of DNA and RNA and the processes of transcription and translation of protein synthesis. What is DNA? DNA is a nucleic acid that carries the genetic information in cells and some viruses, consisting of two long chains of nucleotides twisted into a double helix and joined by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA sequences are replicated by the cell prior to cell division and may include genes,…

add phosphatic groups to the molecule. The molecule becomes effective for the treatment of Hepatitis C virus only when Sofosbuvir as a prodrug is converted to Sofosbuvir as a drug. The drug needs to enter the Hepatitis C virus by disrupting the replication of the virus so that the drug can be an effective drug. Sofosbuvir needs to have three phosphate groups to be effective. Usually the first phosphate is harder to be added but the two others are added readily to Sofosbuvir and make the prodrug…

properly study and analyze a covariance stationary time series, we need to know something about the correlation/covariance structure. Several methods exist for dealing with serial correlation. Here, we will deal exclusively with batch means, replication/deletion, and the Mean Squared Error Reduction (MSER) technique. The goal of these methods is to produce valid confidence intervals (CI’s) in the presence of serial correlation. In our analysis, we will use the lag k autocorrelation to find a…