Revolution against the basic evolutionary developmental biology arises with the astounding repair capacity of the planarian robust self assembly system and its automatic repair ability of its body structures. With its complex body plan and nervous system, a planaria possess the ability to flawlessly regenerate any part of their body after a traumatic injury or loss. It is capable of recovering its original structure and function of any damaged or obliterated body part even after being deprived…
Regeneration of the axolotl is dependent upon the blastema (Aguilar et al 2015). The blastema formation takes place during dedifferentiation. (Satoh et al 2010). The blastema is formed from progenitor cells in the uninjured limb by re-expressing embryonic genes. The origin of these blastema cells are controversial, as many have a hypothesis of where are originally derived. (Whited & Tabin 2009). For instance, Aguilar et al (2015) suggests that the formation of the blastema is dependent on nerve…
Introduction The infection at the wound site is a severe kind of problem and it delays regeneration of epidermis and dermis in the wound and slows wound closure. Due to the secretion of microbial enzymes by wound pathogens, a variety of extracellular matrix proteins were degraded. Synthetic antimicrobial therapy used in the wound management and eradication of pathogens. However, it has many shortcomings such as anti-microbial resistance, cyto-toxicity against host tissue and absence of…
who worship him to bury themselves alive along with a mysterious object that continuously bleeds without stopping. Then, in the year 2006, Todd Maddox is hired by Richard Ridley to work in his company Manifold Genetics as a researcher of human regeneration, mainly focusing on the Hydra, a mythological creature that Hercules fought during the second of his nine trials. Then, archaeologist Dr. George Pierce, who believes that Europeans had been to America long before Christopher Columbus,…
326 genes when regenerating their tails. This includes genes involved in embryonic development which is a response wound healing. Regeneration also doesn't happen quickly; lizards take over 2 months to regenerate their tails. Lizards regenerating structure is very complex with cells growing into tissues along the tail. One cell that has been discovered for regeneration is satellite cells. They develop into skeletal muscles. Since…
are part of an integrated approach adopted by many European cities in the 1990s, factoring in neighbourhood renewal, social inclusion and community involvement (Raco and Imrie, 2003). This was part of a new form of urban governance were urban regeneration projects could be compartmentalised into a series of manageable tasks (Raco,…
practice has been greatly limited to the spinal cord and peripheral nervous system. As such, the main focus of this paper is in the various formats that have been implemented in the past, and current methods employed today in order to facilitate nerve regeneration within the peripheral nerves.…
Since the mid-1800’s, research contributing to the vast amount of information we know today about stem cells has broadened our horizons in the field of medicine, as well as led to several discoveries involving humanity’s origin. Although they comprise only a small portion of known stem cells, muscle stem cells are indeed equally as important to science because of their aid in helping us to gather new facts about the human body. Therefore, to completely understand how these cells affect our…
The doctrines of repentance, justification, regeneration, and sanctification are each a part of the ordo solutis, or the order of salvation. They are each a part of the journey toward the “restoration of God’s image in our lives” (Book of Discipline ¶102 50). They each speak of a salvation that is not a onetime event, but is marked by a lifetime of faithful response to God’s grace. That is another characteristic they each share: they are all preceded and facilitated by God’s grace. God’s loving…
Pilkus’ studies focus on the conversion of a cell lineage of wound myofibroblasts to fat cell precursors in adult mammals using differing mice lines that allow for the manipulation and exploration of fat cell regeneration throughout the wound healing process. To begin the study, it was necessary to explore the components of making the fat cells and their precursor cells during wound healing. Preliminary experiments were conducted using dermal cells from wounds with and without hair follicles.…