Red blood cell

Georgieff, 2009). Iron is a key component of hemoglobin, which is the protein responsible for creating healthy red blood cells (RBCs) and allowing RBCs to carry oxygen (Abbaspour, Hurrell, & Kelishadi, 2014). Consequently, if not treated, iron deficiency can often lead to a life-threatening condition called anemia, which occurs when there are not enough red blood cells to carry oxygen to cells in the body. Since neonates accumulate the majority of their iron in the third trimester, week 28 of…

where it facilitates the active transport of oxygen throughout the body. However, the function of this micro nutrient is not limited to its function in the red blood cell; it is also an important part of different enzymes as well and initiates various essential biological processes in our body. Iron plays an important role in changing blood sugar into a form of energy for the body. Iron aids in immune system health and strengthens cognitive function. Healthy skin, hair and nails, all require…

Sickle Cell Anemia Dakoda Howard Indiana State University Pathophysiology 11/10/2016 Abstract The aim of this paper is to help individuals who do not understand or want to better their knowledge in Sickle Cell Anemia (SCA). SCA is commonly referred to as Sickle Cell Disease or SDA. The area of target is a general overview of that SCA, along with the various amounts of complications that can arise when someone has the disease. The paper will go over some of the more life threatening…

With blood smear analysis they were able to see that the mice studied showed the same effects expected to see in thalassemic patients. Red blood cell count, hemoglobin, hematocrit, red cell distribution had all decreased significantly were as reticulocytes, which are immature red blood cells without a nucleus in thalassemic mice when compared to the wild type. Using dual energy x-ray absorptiometry, they found that in the trabecular sites such as the femoral metaphysis, tibial metaphysis, and…

Thalassemia is known to be an inherited genetic blood disorder that results in mild to severe anemia due to the abnormal formation of hemoglobin. Thalassemia is inherited by either one or both parents. A mutation in either chromosome 11 (Deisserot et al, 1978) effect the synthesis of beta hemoglobin, whereas a mutation on chromosome 16 affect the synthesis of alpha hemoglobin(Deisserot et al, 1977). Hemoglobin is a tetramer made of two alpha chains and two beta chains (Cao et al, 2010). The…

Even today, we see adaptations that may affect someone in your own family. In central Africa, those who carry the sickle-cell gene in populations that are exposed to malaria are immune to the sickness. Another most common is lactose production. Populations with a long history of cattle herding and milk consumption, metabolize lactose is maintained into adulthood. When we…

Haemoglobinopathies Bain (2011) defined Haemoglobinopathies as diseases caused by inherited globin synthesis disorders and thus affects the haemoglobin protein of the blood and its function. It can be argued that haemoglobinopathies are the most common gene recessive disorders in the world (Streetly and Dick 2005). In Australia, the increase of cases with haemoglobinopathies disorder is due to immigration of ethnicities that belongs in the risk list (Metcalfe, Barrow-Stewart and Campbell 2007).…

Plasmodium parasites that can be deadly (Lee, 2018). Sickle cell anemia is a form of anemia where an abnormal hemoglobin changes the shape of the red blood cells. Whether or not you have sickle-cell depends on your genotype. Individuals who have the genotype AA (HbA) have "normal" blood and no mutations which can lead them to contracting malaria more easily because they don't have protection. People with the AS genotype, (HbA & HbS) have the sickle cell trait because they have one normal…

progress has been made in understanding the disease, additional work and development is required to better understand and treat it. Pernicious Anemia According to USNLM (par. 1), “anemia is a condition in which the body does not have enough healthy red blood…

itching and swelling of the skin. Acute porphyria can develop quickly and last for days and for weeks. Other symptoms are abdominal pain, often severe, chest pain, increased heart rate and blood pressure, muscle weakness, nausea, vomiting and constipation, and some urinary retention with the urine becoming red or brown in color. On the more extreme side of the effects of some porphyrias are symptoms such as seizures, increased hair growth, scars and skin color changes, extreme tightening of the…