Receptor antagonist

LC neurons during an aversive event to enable threat learning. To test the hypothesis that orexin carries information important for aversive memory formation, they blocked the OrxR1 activity of an auditory threat conditioning paradigm. The OrxR1 antagonist SB 334867 was administrated by intracerebro-ventricular infusion before fear conditioning and conditioned freezing behavior was examined. Here, a freezing behavior is considered to be a general reaction to perceived threat in a long-term…

Genre Analysis: Three Different Voices of Retrograde Amnesia The main purpose of writing in psychology is to share existent or new knowledge in the field with a wider audience. Since many psychology-related research are conducted within institutionalized laboratories, only a selective group of people, such as researchers, research assistants, and research review board members know about the conducted research’s progress. Therefore, scientists, who obtain respectable degrees, usually write…

Naloxone in the form of a nasal spray Narcan. Narcan is a fast acting antagonist that almost instantly reverses the effects of an overdose by attaching to the opioid receptors in the brain and blocking the opium from having an effect on the nervous system. It is a miracle drug that has saved countless lives yet finds itself in the middle of a law enforcement debate on whether it is the duty of all officers to carry the antagonist. Narcan typically costs $75 for a pack of two and are provided…

All those who are intubated must be extubated! Anaesthesia is a science but learned and practiced as an art. Contrary to its traditional image, functions of modern day anaesthesiologist expands far beyond the boundaries of anaesthetizing and de-anaesthetizing a particular patient. Taking utmost care of the patient and safeguarding the patient from possible untoward events during anaesthesia and surgery is the supreme duty of the anaesthesiologist apart from optimal pain relief to the…

boosts neural activity. Caffeine has a very similar structure to adenosine. Because of this, caffeine is able to act like adenosine and bind at its receptors, thus inhibiting the effects of adenosine. In this way, caffeine is considered an antagonist drug, which is defined as “a drug that blocks or dampens a biological response by binding to a receptor.” Caffeine takes the place of adenosine, and stops the biological response of sleep. This is a desired effect, for example, to stay awake longer…

limited the users drug cravings and would not allow the user to get high on regular forms of opiates. This was because the actual active ingredient in methadone is a man-made chemical that still utilizes the brain’s morphine receptor while also blocking the natural receptor from identifying and utilizing natural opiates - the process is referred to as “synapsis.” Because this new drug allowed the policing of the actual neuron where opiates were broken down in the brain, this brought a new…

MATERIALS AND METHOD FOR BURN SCAR BIOMECHANIC BURN WOUND GENERATION All experiments and data collection were performed following approved protocols of the Ohio State University Institutional Laboratory Animal Care and Use Committee. A female red Duroc pig was maintained on standard chow ad libitum and being fasted overnight at other piggery. The animal had been anesthetized with Telazol and isoflurance. Anesthetic is a rapid and reversible drug-induced change in behavior or perception. Then…

My interested in health profession began, especially in the Pharmaceutical field. After I graduated from college, then I started to work as a credentialed trainer in Epic for Valley Health. It was there when I realized that taking care of patient involves teamwork including doctors diagnosing patients’ diseases and prescribing medication, nurses administering doctor’s orders and pharmacist’s verifying the correct dosage and medication. Upon working with an instructional designer who was a…

Experimental therapies for Huntington's disease currently are being tested in animal models and human trials. Therapeutic options include dopamine-depleting agents like reserpine, tetrabenazine, and dopamine-receptor antagonists called neuroleptics. These medications are not to cure but to help with symptoms Long-term use of these drugs may carry a high risk of adverse effects. Choreic movements in patients with Huntington's disease should be treated pharmacologically…

Fish’s consist of a diverse amount of species each known for their characteristics that set them apart from the rest. The characteristics that make the general understanding of a fish are, vertebrate, aquatic, Gills rather than lungs, paired limbs(fins) for locomotion, and are covered with scales. When we see fishes in aquariums we have an irresistible urge to tap the glass, and in doing so, a lot of the fishes get startled and move away performing a sequence of steps called an c-start used as…