Receptor antagonist

of nicotinic acetylcholine receptors (nAChRs) early on in the progression of the disease (Okada et…

These receptors are found in the cardiac muscle and their stimulation has a positive inotropic effect (increases the contractility of the heart). It does so without significantly increasing heart rate or affecting peripheral vascular resistance (as it does not activate alpha adrenergic receptors of blood vessels). The result is increased cardiac output via increased stroke volume (Tariq & Aronow, 2015)…

unfortunately, two thirds of this population are between 12 and 17 years old (Sofuoglu, Sugarman & Carroll, 2010). Marijuana contains an active ingredient, tetrahydrocannabinol (THC) which alters the human central reward pathway by stimulating cannaboid receptors in the place of anandamide, a hormone of the endocannabinoid system, ultimately causing a sense of euphoria, a common attribute of other abused…

My research interests are focused on molecular mechanisms of memory formation during infancy. I’m very interested in exploring how experiences during infancy results in hippocampal long-lasting changes, which influence adult behavior. Traumatic early life experiences can predispose individuals to psychopathologies, including post-traumatic stress disorder (PTSD), borderline personality disorder, addiction, depression and anxiety1-4. Paradoxically, episodic memories formed during infancy are…

coming off. Ibogaine acts on almost all receptors in the brain, but primarily the…

Legendary musician Bob Marley once said, “Herb is the healing of a nation, alcohol is the destruction.” Bob Marley believed that smoking marijuana opened up a spiritual gateway leading him to become one of the greatest musicians and poets to live. A lot of people other than Bob believe that marijuana can be the answer to a lot of the world's problems. Many cannabis users today argue for the legalization of medicinal and recreational use of marijuana. Marijuana is shown to help with many…

anti-bacterial. Terpinolene has sedative effects. Outside the body it has shown to be a repellant of mosquitoes and weevils. Linaool Also found in lavender. Relieves anxiety and stress. Is a strong anticonvulsant and is said to amplify serotonin receptor transmission. Linaool has antidepressant effects and is effective topically to heal tissue and reduce scarring. Phytol Phytol is unique from other terpenes, offering other medical options. Phytol is the byproduct of decomposed chlorophyll.…

1ml per sample. The samples were incubated at 4⁰C overnight. The following day, the samples were washed with DPBS at 4⁰C and then washed with 2ml 1 perm buffer twice. Anti-mouse Foxp3- PE Ab was added in a 1:100 dilution for 30 mins at 4⁰C. The samples were washed with perm buffer and resuspend in DPBS for flow cytometry analysis. Table 2.4 Antibody panel for SHPS-1 Phenotyping Panel PerCP FITC APC PE PB DC 1 CD45 CD11b CD11c CD103 B220 DC 2 CD4 CD11b CD11c CD8 B220 Treg CD3 CD25 FoxP3 CD4…

Did you know that whenever you smell something, it triggers your senses, and the brain? There are five senses, and one is smell. The brain is a important organ in our body, it tells our body what to do, and what to not do. The person who studied the senses was Linda B. Buck, and the people who studied the brain was the Egyptians. Your senses let you know what is going on around you. The brain is the control center of the body. All information we have about prehistoric cultures comes from…

1. A perception is when sensory impulses are interpreted in the brain, such as touching a hot stove. A sensation is when the brain becomes aware of a stimulus, such as pain. 2. Pain receptors are excited by any type of tissue damage. 3. Referred pain is a phenomenon when you feel pain in an area other than where the pain originates from. 4. The thalamus and cerebral cortex are the parts on the brain that interpret pain impulses. The thalamus establishes the awareness of pain, and the…