Reagents for organic chemistry

The results obtained for this lab were very unsatisfactory, even though the results sustain a general trend throughout the course of the experiment, the results were not expected. At the beginning of the experiment all reagents produced satisfactory results, the reactant 2-bromopropane was determined to be the limiting reagent for the Grignard formation and the Isopropyl Magnesium Bromide was correctly formed. However, random errors occurred at the nucleophilic addition step. At this period, it was observed there was not condensation happening inside the reflux condenser while the mixture was being heating, and as a result, the nucleophilic addition was not successful because some of the product was lost through boiling without condensation.…

AHHHH CHOO-DOEPHEDRINE Although, originally defined as the chemistry of biological structures, organic chemistry has since been redefined to refer specifically to organic (carbon based) molecules. The hydrocarbon is the very basic molecule of organic chemistry and by adding functional groups to the hydrocarbon we can manipulate the properties of the molecule. Through the manipulation of these organic compounds, organic chemistry can be used to chemically synthesise many products such as soaps,…

In SPOS, an excess reagents are used to drive reaction to completion, and products can be easily isolated by simple filtration from solid support.1 Other benefits of solid-phase is the ease of automation and the ability of polymer to “fish out” low concentrations of product molecules from excess of starting material.2 Heterocyclic compounds usually serve as a backbone of hundreds of marketed drugs.3 In this respect, we have been interested in thiazolo[4,5-b]pyrazine core skeleton. Even though…

I see many issues as a threat to our community of transfer students and I as a transfer student can empathize with them on some of these issues. One issue is lack of knowing the vast resources that UMD provides for its students. Many transfer students come to UMD and notice that it’s nothing like their community college they are exposed to differences in class and campus size, academic rigor, etc. The fact that many transfer students don’t know the various resources that UMD offers such as…

Kyle Rohl Chem 3520 Nobel Prize Paper Chemicals in 3D Vision The Nobel Prize in Organic Chemistry for the discovery of chemicals in 3D vision was awarded to Derek Barton and Odd Hassel in 1969. This was the breakthrough in visualizing the way chemicals could be interpreted. Before their phenomenal discovery, people could only think of seeing a chemical such as cyclohexane in its planar, flat, 2D form. What Barton and Hassel found that was different from the universal perspective of this…

researching for an effective drug against an unknown target, three structures were synthesized, when comparing the structures researchers realized that optimal performing substituents on one structure can have different or lower results in other similar structures. For instance, the chloro substituent was optimal in the tricyclic molecules, but the nitro group was optimal in the bicyclic Oxamniquine molecule. To date, a drug called Praziquantel has been synthesized that is effective against…

In Period 11 of lab, two experiments were conducted: one investigative and one preparative. Both experiments demonstrated the theory and concepts behind electrophilic aromatic substitution. As the term states, the experiments deal with the chemistry of six membered ring compounds and their transformations through electrophilic substitutions. This type of reaction transforms the aromatic compound by allowing various functional groups to be attached to it. The general process of this reaction is…

During the Winter Quarter of 2018, I enrolled in CHEM1A at De Anza Community College to deepen my understanding of chemistry. Going into the class, I expected it to be similar to a high school class. However, I quickly discovered that it was quite different--it was literally and figuratively in a class of its own. There were a lot more advanced concepts taught in my CHEM1A course. At first, I was at a loss on how to study and adequately prepare for the class, given the volume of material and…

PRINT YOUR OWN MEDICINE Chemist Lee Cronin is a professor of chemistry and nanoscience and chemical complexity. He founded the Cronin group who is focused on complex functional molecular architectures that are not based on biologically derived building blocks. Cronin’s idea is to “app” chemistry and by this he means making a “really cool universal chemistry set”. He speaks with confidence to a mature audience that has an interest in the future of chemistry and medicine and those who create or…

This experiment was conducted to practice a variety of techniques in organic chemistry: separation, mechanisms, acid-base reactions, evaporation, recrystallization, and identification. The goal of this experiment was to identify the unknown mixture of two compounds. The two compounds were separated first by altering the acid components solubility through deprotonation, and then protonating the acid component again to form the separated precipitate. The ether in the neutral layer was evaporated,…