Introduction: Resistance to antibiotics is an ongoing concern of the pharmaceutical industry. The limited number of antibiotics in the market to treat Gram negative bacteria made their resistance an issue that is being addressed worldwide. The isolation of colistin from Bacillus polymyxa var. colistinus in Japan in 1949 and the introduction of colistin into the market in 1959 as its inactive prodrug colistin methanesulfonate (CMS) were significant milestones in the treatment of this type of…
Sara Parks Unknown Report Introduction One of the many reasons to study microbiology is to gain a better understanding of microorganisms and the huge part they play in the world. It is imperative to know the differences between microorganisms. This knowledge is useful in many cases; for instance, a patient with an unidentified infection could be administered effective treatment if one possessed the knowledge to correctly define the microorganism. Furthermore, the purpose of this unknown…
al., 2011). These characteristics of siderophore are arises due to its ligand functionalities and with the help of this property siderophores may have a strong binding affinity or selectivity to metal other than Fe (Hernlem et al., 1999). Pseudomonas aeruginosa secrete the pyochelin siderophore and could chelate various types of metals, e.g. Ag+, Al3+, Cd2+, Co2+, Cr2+, Cu2+, Eu3+, Ga3+, Hg2+, Mn2+, Ni2+, Pb2+, Sn2+, Tb3+, Tl+ and Zn2+ (Braud et al., 2009a). Both types of siderophore (Phyto and…
It is conspicuous from various studies that the metal based nanoparticles is found to be an effective antimicrobial agent against several common pathogenic microorganisms.(Nanoparticles and potential apps, Biomedical applications,Antimicrobial activities of silver nanoparticles, Green synthesis, A review on plants extract mediated, Antimicrobial Properties).It is multidisciplinary area where in nanotechnology has led to major developments in health and medicine due to the integration the…
This lab experiment was completed to determine the environment in which microbes prefer to live. The pH, moisture, available nutrients, oxygen and light all affect the rate in which bacteria grow. The majority of bacteria flourish when the pH level is near neutral; the growth rate is highly affected if the pH is off by just a little. If too acidic, the amount of time it takes the bacteria to adjust to a new environment (lag time) is increased which slows the growth, the activity of enzymes is…
to arise until the child is older. Normal symptoms include coughing up blood filled phlegm, “recurrent bronchial infection” (Hopkin 1991) and “progressive bronchiectasis” (Hopkin 1991) both of which normally occur from the “bacterium called Pseudomonas aeruginosa” (Christensen 2002) due to their in ability to expel the mucous. In addition to this many people with Cystic Fibrosis also normally experience “excessive inflammatory response to pathogens” (Davies et al. 2007). With regards to what was…
1. Introduction L-Ornithine is an important chemical ingredient for its applications in food and pharmaceutical industries as a dietary supplement, as it is known to be efficacious in the treatment of liver diseases and wound healing [11]. It can also be used as a precursor for the synthesis of other amino acids, such as arginine and citrulline, and putrescine, an important diamine used as a nylon precursor [28]. L-Ornithine could be produced by fermentation using auxotrophic mutants, for…
appeared clear with an outline, and the spores that were seen appeared as black dots. c. The first test performed was the gram stain, the purple color indicated that it was gram positive, this removes all gram negative possibilities including Pseudomonas aeruginosa, Klebsiella pneumonaie, and Proteus vulgaris. Since I also observed that the bacteria were rod shaped, it excluded the cocci specimens Staphylococcus aureus and Streptococcus pyogenes. After performing the spore stain and noticing…
from the soils of Bikaner, Rajasthan and was added to a mixture of silver nitrate to form silver nanoparticles [5]. The AgNPs synthesized were found highly toxic against many different multi-drug resistant human pathogens: Escherichia coli, Pseudomonas aeruginosa, and Streptococcus aureus. These silver nanoparticles even exhibited greater antibacterial activity than standard antibiotics [5]. This investigation showed how bacterial endospores have the potential of being excellent bactericidal…
URINARY TRACT INFECTIONS Abstract UTI is one of the most common infection to affect people all around the world in today's world, putting a huge load on the health care system cost wise. Because this problem is so common and so significant in routine clinical practice, a high level of diagnostic accuracy is essential. The urinary tract infection (UTI) which involves urethra, bladder or kidneys can be infected, the majority of UTI are not serious and can be treated by antibiotics but if not…