Protein structure

elaborate on the role of aqueous humor and vitreous humor in maintaining the pressure of the globe, the structures related to the humor, functions of the humors, origin and also pathology related to them. PHYSIOLOGY OF THE AQUEOUS HUMOR The aqueous humour is a transparent fluid similar to plasma, but containing low protein concentrations. It is secreted from the ciliary epithelium (a structure supporting the lens). It is located in the anterior and posterior chambers of the eye, the space…

The lack of antioxidant cause oxidative stress and excess free radicals that peroxide cell membrane and destroy it; break and even mutate double-strand deoxyribonucleic acid; change the structure of proteins and make the function exception. H. sabdariffa extract has been determined as a useful antioxidant, and we detected the reducing power capacity and expected had sound effects. We used BHA (100 µM) as standard and dilute the sample to designated…

CreCom™ Complement Therapeutic Services. Systemic lupus erythematosus-like syndrome Staffed by dedicated scientists with combined knowledge and expertise in antibody engineering and protein X-ray crystallography, Creative Biolabs has extensive experience in crystallizing antibody-antigen complexes and resolving their 3D structures. Based on our extensive knowledge, we are fully equipped to reach out to our clients who may have the problem or difficulty dealing with epitope mapping. The immune…

vasoconstriction in the bleeding phase. Vasodilation will stress as far as opening previously dormant capillaries. (Reference) The increasing blood flow to the area is due to the vasopermeability caused by histamine (Watson, 2012) and will allow protein rich plasma into the interstitial space along with water (due to osmosis). This then assists in the cellular cascade as cytokines stimulate the white blood cells such as neutrophils and macrophages to enter through the walls to the damaged area.…

Introduction An enzyme is a protein that functions as a catalyst, it speeds up chemical reactions (Freeman et al. 2017 p. 90). Enzymes are often large globular proteins and are able to hold substrates in specific orientations so they are able to react, the location where the substrate binds with the enzyme and reacts is called the active site and is the location where the catalysis occurs (Freeman et al. 2017). Enzymes activity is often related to the optimal environment for them in respect to…

recent research has focused on developing antibody drug conjugate to target HRS cells (Foyil and Bartlett, 2010). A monoclonal antibody against CD30 conjugated with drugs has been tested with patients and has showed promising result. H2A.B is a protein, which is specifically expressed in HL pathogenic cells. Understanding of H2A.B functions in HL cells may contribute to our overall understanding of HL and the development of potential cures in the…

deep and narrow binding site used to recognize smaller aromatic molecules and another more prevalent isomer with a wide and shallow binding site that enables the antibody to recognize several different protein antigens14. Due to this conformational isomerism phenomenon, the dynamics of this structure allows for SPE7 to bind to several different types of antigens16. In addition, the less prevalent isomer of SPE7 that utilizes induced-fit binding allows for several different antigens to be…

which play a vital role in both mitosis and cytokinesis as they give cilia and flagellum the ability to generate motion and they ensure both newly formed cells contain paired centrioles during the later stages of cell division. Kinetochores are protein structures that produce chromosomal movement through the attachment of chromatids to spindle fibres and aid in cell division. Paired chromatids attach to two different kinetochores (I and II) which then connect to spindle poles via the spindle…

RESULTS Phytic Acid The concentration of phytic acid was determined spectrophotometrically in three tested plant materials of Gishta as shown in table 2. The concentrations of phytic acid were obtained from 5 g dried leafy material. All the leaf samples contained phytic acid (detection limit 0.025 mg/ml) in this study. This may have been due to the fact that there was a limitation in terms of the detection concentration since concentrations less than mg was not tested. Seed extracts was found…

This agents mainly target (1,3)-b-D-glucan synthase which plays an important role in the synthesis of cell wall component of pathogenic fungi such as Candida spp. and Fusarium spp. That leads to disruption of the growing cell wall structure, resulting in osmotic instability and death of susceptible yeast cells. The target of echinocandins was not present in mammalian cells, so there is minimum toxicity of drug. There is an activating and a catalytic subunit of β (1-3)-glucan synthase…