Pre-clinical development

The tradition of beginning an engagement with a diamond ring is largely an American custom that has resulted in the United States becoming one of the largest shareholders of the global diamond jewelry market (Global Diamond Jewelry). The custom dates back to first half of the 1900s when diamonds were introduced as a symbol of undying love due to their lasting value. Although diamond wedding rings serve as an investment and symbol of eternal love, some luxury rings, such as Tiffany and Company,…

Participants, written by mental health professionals Daniel Bowena, James Neilla, and Simon Crisp (2016), is an evaluation of 36 adolescents participating in a ten-week Wilderness Adventure Therapy (WAT) program in Australia. As young adults make up a large clinical population, many interventions are designed for younger children or adults, so this article begins by expressing the need for therapeutic interventions specifically designed for adolescents (Bowena, Neilla, & Crisp, 2016). Bowena et…

receive Master’s degree in Clinical Trial. I became interested in Clinical Trials after noticing the importance of clinical research. The initial interest developed when I started working at clinical research organization at the administration office. Many new things I got to know from the first months of working there. I became motivated from reading articles and learning new things from my colleagues. We are in an era of specialty pharmaceuticals – new drugs and clinical trials have not…

aspect of the clinical trials that help determine their relevance in regards to research and development. It is the outcome by which the effectiveness of treatments in a clinical trial is evaluated. Because of its importance, it is essential for primary endpoints to be concisely and carefully specified to ensure that the results will be accurate and accepted in the scientific community. They must possess important characteristics that ensure qualitative endpoints are chosen for each clinical…

Greek philosophy is widely considered as the beginning of organized Western thought. Mathematics, science (including biology, cosmology, and physics), political theory, psychology and more were all developed in the Greek era. Ancient Greece’s influence on philosophy is so abundant that the works of Plato are often considered the footnotes of western philosophy. In making such a bold conviction it is only to say that Ancient Greece marked the starting point for Western philosophy. In this paper I…

A. Commander Involvement and Support: Complies: The commander, Major Derek Williamson, is actively involved in his unit’s safety and health program. He has issued a commander’s policy on safety and developed unit mishap notification procedures. His priorities and expectations for safety are stated clearly. Maj Williamson frequently conducts meetings in which the Unit Safety Representatives brief current safety items such as unit mishaps and open discrepancies. B. Unit Safety…

Dante Rossetti’s, Jenny: A Cautionary Tale of Sexual Knowledge and its Destruction of Women “The whole education of women ought to be relative to men. To please them, to be useful to them, to make themselves loved and honored by them” - John-Jacques Rousseau England in the 19th century was wrought with the battle for women’s rights, specifically the education of women. In his poem, Jenny, Dante Gabriel Rossetti’s narrator makes various references to books – those on his shelf, and how…

By nature, every single person ever created was born with different views and ideas. There may be groups of people that agree on certain subjects and ideas, but not everyone is the same. From what someone automatically thinks of when they see a painting to how they interpret a work of poetry. The words, thoughts, and images that come to one's mind differ from the many other people in the world. ☆In the painting, Circe Pouring Poison Into a Vase and Awaiting the Arrival of Ulysses, Sir Edward…

RWE – For better accessibility of drug treatments Thinking Beyond the Clinical trials Though clinical trials are the gold standard measuring the safety and efficacy of drugs, to evaluate the cost-efficiency of a drug in a real-world environment and measure its impact on quality of healthcare, RCTs need to be supplemented or followed up with the comparatively new standard, called real-world evidence (RWE). Real world evidence has is entering every part of the drug product life cycle from…

Pharmacogenomics and its application in drug development 1. Drug target and Pharmacogenomics: The very initial step of drug development starts with identification of the rug targets. These targets may be recep0tors, enzymes, transporters, ion channels etc. 8000 drug targets were estimated after sequencing the human genome. Among the 2392 actually…