10 minutes prior to a liquid meal. Nateglinide did not have any effect on gastric emptying in healthy subjects as assessed by acetaminophen testing. 3.6 MECHANISM OF ACTION Nateglinide drug is fixing on specific receptors and acts through the potassium channel from the pancreatic and the extra-pancreatic level. At pancreatic level, increase insulin secretion and at the level of pancreatic beta cells, they increase the number of insulin receptors. At extra-pancreatic s nateglinide decreases…
see symptoms of rhabdomyolysis. Nontraumatic exertional rhabdomyolysis occurs when normal muscles lack the energy supply to meet demands. Rhabdomyolysis may arise if a person is physically untrained, exhaustion from heat, and hypokalemia caused by potassium loss from sweating. Nonexertional and nontraumatic causes include “drugs, toxins, infection, electrolyte abnormalities, endocrinopathies, and inflammatory myopathies.” Prescribed medications, drugs of abuse and alcohol can cause…
Measurement of glutathione Glutathione (GSH) is a ubiquitous tripeptide which serves several vital functions including detoxifying electrophiles, scavenging free radicals and providing a reservoir for cysteine. The sulfhydryl group of GSH reduces 5-5'-dithiobis (2-nitrobenzoic acid) (DTNB) and form the yellow colour product 5-thio-2-nitrobenzoic acid (TNB)21. Measurement of the absorbance of TNB at 412 nm provides an accurate estimation of GSH in the sample. Figure 7. Materials 5×105 cells/mL…
The Chemistry of Baking If there is one thing in the world that brings people together, it is food. No matter who a person may be, or what their background is, everyone can enjoy an excellently crafted dish. In particular, many people enjoy selections of pastries, sweets, and bread. There are hundreds to thousands of crafted desserts and bread around the world. When a person first bites into a macaroon, slice of asiago bread, or a perfectly-shaped chocolate chip cookie, they might not consider…
The most intriguing patient during my time at Decatur General Hospital was a man who was admitted with rhabdomyolysis. The patient is a 68-year-old male with a significant past medical history of hip fractures, decubitus ulcers along with sepsis, alcohol abuse, acute blood loss anemia, gastroesophageal reflux disease (GERD), and nicotine abuse. The patient was transferred to Decatur General Hospital Emergency Room from his previous rehabilitation center due to progressively getting weaker and…
Ali Dawood grade: 11A Autobiographical Narrative ?Final Submission- ----------------------------- The Chemistry Clash of Ali Dawood During my rather long and tedious childhood, in which I had to go and get laughed at due to my poor -at best- academic performance, I was always fascinated by teachers, they seem as if they knew everything, seriously for a first grader they surely did! Especially the science teacher Nasser Al-Baba, I would go and attend his class from the window overseeing the…
List A: Microbiology of Inflammatory COPD Exacerbation Microbiology Results Indication Sodium Level 142 mmol/L Normal Potassium Level 5.1 mmol/L Normal Chloride Level 101 mmol/L Normal Bicarbonate Level 29 mmol/L Normal Urea Level 7.3 mmol/L High (2.9–7.1 mmol/L) Creatinine 91 umol/L Normal eGFR CKD-EPI 73 mL/min/1.73m^2 Normal Bilirubin Total 10 umol/L Normal Protein Total Level 68 g/L Normal Albumin Level 28 g/L Low (35–55 g/L) ALP 68 U/L Normal GGT 16 U/L Normal ALT 29 U/L Normal AST 22…
end products of metabolism and substances that have accumulated in the blood in undesirable amounts during the filtration process. Substances removed from the blood include urea, creatinine, uric acid and urates. Undesirable amounts of chloride, potassium, sodium, and hydrogen ions are also filtered from the blood. The glomerular filtration rate (GFR) is amount of the fluid filtered each minute by all the glomerular of both kidneys and is one index of kidney function. * Excretion - The kidneys…
assessment 2 case study In this essay, Annie is a 44 year old lady having a female partner (wife) and a 3 year old son. Her partner is working in mines and living away from them. there is no body to help Annie and to take care their son in her absence. Annie is admitted to emergency department complaining of exacerbating pain in her right big toe from last couple of days. she explain that pain is so severe that she could not sleep for last two days as she had to sleep with her right foot on…
Animals and treatment Male Wistar rats were purchased from National Institute of Nutrition, Hyderabad, India and the study was strictly done under the guidelines approved by the animal ethical Committee of CSIR-Institute of Genomics and Integrative Biology, Delhi, India. They were maintained under standard conditions (12/12 hour light/dark cycle at 25±5ºC). They were divided into five groups having six rats per cage and are allowed to acclimatization for 1 week. Group 1(G1) - Healthy control…