Polymorphism

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    The experiments covered in this report are based on the topic of DNA polymorphisms, these according to Houseman (1995) are differences in the DNA that occur between individuals. The polymorphisms under investigation here are classified as VNTR’s (variable number tandem repeats) and RFLP’s (restriction fragment length polymorphism). The first experiment is concerned with DNA polymorphisms that are known as VNTR’s, sections of DNA which have repeated nucleotide base sections in which the repeats vary in number per individual, here the VNTR’s chosen were D1S80 and D3S1358. The second centred on Restriction Fragment Length Polymorphism (RFLP) analysis and how the technique lends itself to the identification of genetic diseases. Each experiment…

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    My Antonia Comparison

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    The Novel, My Antonia, which is written by Will Cather, tells a story about immigration and relationships in Nebraska. The whole story is told from Jim Burton’s aspect, who is the main character. Antonia Shimerda, another main character in the story, moves from Bohemia to Nebraska with her family. She is Jimmy’s best friend, and they both play an important part in each others lives. Their relationship and growth are presented in the book. This novel was adapted into a film in 1995, which is also…

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    Red Hair Polymorphisms

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    Title: HAIR GENETICS A study of DNA sequence variations in melanocortin-1-receptors or MC1R genes found many variants of amino acid found in people who were red-haired but rarely found in the non-red people. Researchers have identified 3 common amino-acid-polymorphisms associated commonly with red haired people viz., R160W, R151C, & D294H. The abbreviated names mean common amino acid types were found in positions 160 151, & 294 in proteins are arginine (R), cysteine (C), arginine & aspartic…

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    Gene Polymorphism Lab Report

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    Association of Gene Polymorphisms and Development of Neurological Conditions Using Restriction Fragment Length Polymorphism Samir Nacer Lab Partners: Krystine Sora, Sierra Sandler, Ali, Alfredo Lam, Natalia Figueroa Biology 3600 Genetics I with Lab Instructor: Dr. Robert Smith Laboratory Assistant: Eileen Date of Experiment: November 7th, 2016 Abstract: A migraine is a neurological condition in which blood vessels dilate causing an extreme aching pain on a specific side of the human skull.…

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    profiles of individuals. The primary purpose of a DNA database is to ease the identification process of suspects during criminal investigations. Despite the intention to do good, the concept of a DNA database is vulnerable to a number of complications and repercussions, affecting the government, general public and crime detectives. Biological Significance DNA Profiling is a forensic process utilised to identify individuals by the characteristics of their DNA. It differentiates from other…

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    repeats blocks that are spread throughout the genome. (2016, Encyclopædia Britannica, Inc.) DNA fingerprinting is widely known to be used in criminal investigations. To see how well a suspect’s blood or any bodily material is closely related to evidence that may have been found on the crime scene, DNA fingerprinting allows investigators to evaluate just how well they match. Established in all states, there are DNA fingerprint databases, which all states require the collection of DNA from…

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    DNA fingerprinting is a method where a collection of fragments of DNA found at a crime scene are used to match other fragments of DNA. It is used in crime cases when visual identification is not available and aids in determining whether the suspect is present at the crime scene or not by using bodily fluid (saliva) or blood found at the crime scene. It can also identify the victim whose body is disfigured. The concept that everyone has different genetic code except for identical twins is really…

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    Vaccine Analysis Case

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    used to cleave DNA into smaller fragments for analysis and began using bacterial enzymes for such purposes (tech). When conducting this lab, it would have been difficult to provide evidence against one of the suspects if only one enzyme was used. For example, as enzyme 1 cleaved the DNA of both suspects at the same location, not enough genetic information was being analyzed in order to rightly accuse the suspects of the crime. Thus, it is very important to use a variety of enzymes. Primarily,…

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    DNA (deoxyribonucleic acid) is the genetic material that carries the genetic instructions being used in growth, development and reproduction of all living things. DNA has regions called genetic polymorphisms that are used to determine paternity/maternity, kinship, determination of human remains, and inherited diseases. DNA is an example of what forensic use for evidence in a crime. Using regions in the DNA you can determine a “fingerprint” for an individual that can help in a crime, with this…

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    The gel electrophoresis apparatus is then turned on and the DNA begins to migrate from the negative side to a positive, which is due to DNA being negatively charged. This process takes Restriction Fragment Length Polymorphisms (RFLPs) and migrates them. The longer the RFLP, the slower it moves and the farther it is up on the gel. The short the RFLP, the faster it travels and the lower it is on the gel. After the gel is ran, it needs to be analyzed to determine whose DNA it belongs to.…

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