no shifting of peaks of metronidazole i,e., characteristic peak of the amine group (N-H streching) present in imidazole nucleus at 1030 cm-1 and presence of NH2 group at 3298 cm-1 in formulation. Hence, there was no interaction between drug and polymer. 6.2 METRONIDAZOLE MICROSPHERES 6.2.1 Optimization of speed (rpm) for preparation of microspheres Metronidazole microspheres were prepared using emulsion solvent evaporation technique. For optimization of stirring speed, the microspheres were…
PRE FORMULATION STUDY: Pre formulation testing was an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. It was the first step in the rational development of dosage forms. Class: -Pre formulation study can divide into two subclasses: API characterization, Compatibility study Active pharmaceutical ingredient (API) characterization:- Organoleptic evaluation:-These are preliminary characteristics of any substance which is useful in…
of disaccharides are sucrose, lactose, and maltose. Lastly, a polysaccharide is a polymer of 3 or more sugars formed by a deydration reaction. Examples of polysaccharides are starch and glycogen. In this experiment, central sugars can be found by utilizing Benedict's test. Proteins are made of carbon, hydrogen, oxygen, nitrogen, and from time to time sulfur. Proteins are covalently maintained in chains as polymers of amino acids. These bonds are called peptide bonds. Peptide bonds are the…
Caesar Stone was founded by Amos Amir, Gili Amir's father and CEO of Caesaria Marble, Sdot Yam's floor tiles plant, in the 1970s. Amir had come to the conclusion that the days of Terrazzo flooring, had passed. So he began searching for the next generation of flooring material that was thinner, lighter, and stronger, while being less labour intensive and polluting to produce. …??? Caesar stone is a stone manufactured to create surfaces such as benchtops, splashbacks, bathroom vanities, wall…
The issue of plastic pollution also negatively effects our ocean life, producing diseases and defects in fish and other creatures living in the ocean. These plastic polymers that are ingested by animals are so small that they are almost impossible to see and clean up. These plastic polymers and the chemicals that come with them cause irreversible damage to our oceans and make it an unrealistic option to dispose of the tons of litter. TOXIC: Garbage Island is able to document…
The future in trying to stop concussions still has a ways to go. The future could be as easy as making helmet to helmet hits illegal in the game and penalize the player. And in the pros they could possible fine the players for the helmet to helmet hits which they have started to do. If a player does get a possible concussion scientist are looking into being able to take a quick blood sample on the sideline, like if you were checking blood sugar, and test it to see if the player has an elevated…
Betty Ngo Introduction Macromolecules are the critically important large molecules that fall into four main classes: carbohydrates, lipids, proteins and nucleic acids. Macromolecules are polymers which are built up by monomers. Monomers become polymers from the process dehydration reaction and polymers are broken apart by the process hydrolysis. Macromolecules are critically important to all living organisms because they perform basic functions necessary for an organism to live.…
The resistive component of analysis can also be modeled as a spring in which the spring constant is positively correlated to the force applied to the spring: F= kx, where k = f(x)*Fimpact. The force of impact would mostly dissipate through the springs, and the specific behavior of the springs can be modeled in later stages. The component of force that needs to be looked at primarily is the x component, since this is the component of the force that would produce the most torque on collision.…
Asthma and chronic obstructive pulmonary disease (COPD) are among the most common and prevalent diseases in the world (Raadhika and Shanthi, 2012; Rao and Kulkarni , 2012). Salbutamol sulphate (SS) is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm (Sharma et al., 2015). Salbutamol sulphate is readily absorbed from the gastro intestinal tract following oral administration, and it undergoes the first pass metabolism in the liver. It requires multiple dosing a day…
Kevlar Kevlar (poly para-phenylene terephthalamide) is a registered trademark for para-aromatic polyamide synthetic fiber that contains polymer (multiple chain bonds) which makes it extremely strong. It is flexible, light, and thermal stability allowing this unique synthetic fiber to be used in advanced technology applications such as bulletproof materials. Invention The invention of Kevlar® was developed in 1965 by a chemist, Stephanie Kwolek. Kwolek made the breakthrough while working at…