Final Paper: Measuring Change in HRQoL of ITP Patients in Japan treated by Eltrombopag Introduction Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder, which is characterized by a low platelet count caused by both increased platelet destruction and insufficient platelet production [1]. In Japan, there are 20,000 patients with ITP and the incidence of ITP is estimated at 3,000 per year [2]. Major signs and symptoms include red spots and/or bruising on the skin, prolonged bleeding…
Midterm Exam 1. The leaf cutter ant community is a large amazing system that contains many different species that interact with each other on many different levels. Although many things take place during this extraordinary symbiosis, there are a few keystone mutualists within this leaf-cutter ant community that without them, the results would be almost catastrophic. For one, fungi are extremely important to the ants. Specifically, the fungus Lepiotaceae . The ants cultivate this fungus and…
Cognitive Therapy versus Narrative Therapy for Depression Depression One of the most common reasons adolescents seek treatment is because of depression. According to the literature on adolescent depression, some adolescents are more susceptible to to depression due to genetic predisposition and exposure to significant negative life events (Spirito, et al., 2011). In adolescents prone to depression, stress, typically from an interpersonal conflict, may initially produce a depressive episode…
for the Ebola virus. Specifically, the researchers have to decide if they should do a blinded experiment or a non-randomized experiment. The problem with this choice is that a proportion of those involved with the study would purposely be given a placebo, or no drug. The other option is to give everyone within the study doses of the drug. This has the problem of producing less than accurate results, since data on the trial drug would be mixed with data on previous drugs, thus prolonging the…
“Research is a way to gather information and make a sound decision or judgement or develop new knowledge” according to (Latin and Berg, 2007, p.4). In sports therapy research can be used in a variety of ways for example, a sports therapist may undertake research to find new exercises that strengthen the shoulders, a sports therapist may do this because their client has been doing the same exercise for several weeks and has become bored doing the same exercises. Sackett (1996) states that…
stress-related symptoms. For six weeks, participants either received hands-on Reiki, distance/non-touch, or distance placebo. The participants were tested after the treatment period, and demonstrated that there was no difference in receiving hands-on Reiki versus the non-touch method, but there was a significant difference in reduced mood symptoms compared to the distance placebo. After a re-test one year later, the groups that received either hands-on or non-touch Reiki continued to show…
bases. According to “Randomized, Placebo-Controlled Trial of Exposure and Ritual Prevention, Clomipramine, and Their Combination in the Treatment of Obsessive-Compulsive Disorder,” an article posted in The American Journal of Psychiatry, “Treated and completer response rates were, respectively, 62% and 86% for exposure and ritual prevention, 42% and 48% for clomipramine, 70% and 79% for exposure and ritual prevention plus clomipramine, and 8% and 10% for placebo” (Foa 151). From this data, one…
significantly worse. Jorms continues to state that even if the statistics load positive there is no way if it is due to the treatment given or as just a natural progression. As shown in a paper by Rutherford et al, there is a level of effect that placebo can be placed in relation to treatments such as medication and psychological treatment and which may lead to the interpretation of the data to be slightly biased due to the no collation of remission data (Rutherford et al., 2012). This in…
The fact that the company was overinvolved with the definition of the disorder in order to create revenue for their solution to the “problem” became apparent to Caner when she noticed that the benefits of the drug were unclear in comparison to the placebo and the side effects could be quite negative – yet the company still marketed as a success and a perfect solution, calling it female Viagra and promising to bring its female consumers to orgasm in every sexual encounter with its aid. When she…
1. Describe the clinical trials process of how a drug is approved by the FDA. The clinical trials process can be divided into four phases. Phase one, the researchers recruit a small group of healthy people (20-100 people) into the trial. This phase focuses on absorption, distribution, metabolism and elimination. The small dose will be administered. At the end of phase one, the safe dosage and the best route to administer drug will be set. Phase two is similar to phase one. The difference is…