Philadelphia chromosome

small number of boys have a different MECP2 mutation and can have some developmental delay. Rett Syndrome has an unknown etiology, perhaps because of the lack of bulk investigations available. According to Pellock, there is a mutation on the X chromosome which affects the methyl-CpG-binding protein 2 (MECP2). There are also other mutations that can cause atypical or congenial Rett Syndrome such as mutations in the CDKL5 and FOXG1 genes. These cases may be caused by partial gene deletions,…

Designer Babies Should Not Be Allowed Most people have heard of Build-A-Bear Workshop and how they allow someone to customize a stuffed animal however they would like. Now, imagine doing that with a baby. Thanks to new advances in technology and research, this may become a reality very soon. One such technology capable of restructuring genetic codes in human embryos is the CRISPR-Cas9 method. This works by using an enzyme found in bacteria to snip out segments of DNA and replace the section…

The concept of “blending” as championed by such scholars as Aristotle and Hippocrates states that any trait that an offspring receives is the average of both of its parents. This concept was widely believed until Mendel’s experiments. Incomplete dominance occurs when the heterozygous phenotype is an intermediate between both of the homozygous genotypes. This concept is demonstrated best through the inheritance of petal color in a snapdragon. In a heterozygote the phenotype would be pink, a mix…

Chediak-Higashi syndrome is a Primary human immunodeficiency disease which is caused by genetic predisposition in an autosomal recessive pattern, where this describes any chromosome other than sex chromosomes where both pairs of the gene in each cell have underwent mutation. This disorder itself is a rare one, where about 200 cases of the condition have been reported worldwide. The parents of the person with this type of condition, autosomal recessive, carry one copy of the mutated gene, but…

Trisomy X Trisomy x syndrome, also known as triple x and 47xxx, is characterized by the presence of an extra x chromosome in each cell of a female. Three x chromosomes are present, rather than a normal pair in the nuclei of body cells. The first published report of a women with triple x syndrome was Patricia A. Jacobs at Western General Hospital in Edinburg, Scotland, in 1959. The condition occurs in about 1 in 1,000 newborn girls. Five to 10 girls with triple x syndrome are born in the united…

Domain: Eukarya Giant Pandas belong in this domain as they are composed of eukaryotic cells that have a specific task or function in the body. They are larger cells that possess membrane- bound nucleus and membranous organelles (including endoplasmic reticulum, Golgi apparatus, chloroplasts, and mitochondria). Like a prokaryotic cell, they also possess a plasma membrane, cytoplasm and ribosomes. Aksi giant pandas perform cell division through mitosis and reproduce sexually through meiosis.…

Progeria, otherwise known as Hutchinson-Gilford Progeria syndrome , is a rare disorder that causes children to age eight times faster than a normal person. This disease affect only 350 kids today. It was discovered by Jonathan Hutchinson in England in 1886 and was first called Progeria by Hastings Gilford. It was then named Hutchinson-Gilford Progeria syndrome. The name Progeria is taken from a Greek word that means "prematurely old". It is an autosomal recessive disorder, meaning that an…

Stickler Syndrome is a rare disease due to several mutations in certain types of genes that are involved in the formation of collagen. Collagen is an important building block of connective tissues, which is mostly effected throughout the body by Stickler Syndrome. This disease affects both male and female; the rate is at approximately one to three in every ten thousand births and one within every seventy-five hundred births. Investigators of this disease believe that Stickler Syndrome is very…

Osteopetrosis is a clinical syndrome characterized by the failure of osteoclasts to resorb bone. As a consequence, bone modeling and remodeling are impaired. The defect in bone turnover characteristically results in skeletal fragility despite increased bone mass, and it may also cause hematopoietic insufficiency, disturbed tooth eruption, nerve entrapment syndromes, and growth impairment. Researchers have described several major types of osteopetrosis, which are usually distinguished by their…

is arranged. One of their main function is to contribute/help with processes that involve cellular activities. One example of cell division where centriole plays a role in mitosis where the organelles creates spindle fibres. These fibers allow chromosomes to be separated from each during mitosis and the can create daughter cells. The centrioles play a key role…