Phenylalanine hydroxylase

bacteria or viruses. Meanwhile, a inherited genetic disorder is found in DNA and occurs when inherited by one’s parent. Numerous are caused by transformation in the quality of the cell. Having Phenylketonuria, your body won’t be able to process Phenylalanine, a protein that is in most of the foods. Phenylketonuria is usually found in people from Native American and Northern European ancestry and less common in people from Asia, Africa, or Hispanic ancestry. About one in 15,000 babies is born…

aspartate which has been linked to problems such as memory, weight gain and brain lesions in those subjected to their ingestion (Spatial, 1). Phenylalanine itself can be dangerous prenatally from its active movement across the placenta and postnatally concerning those with phenylketonuria. This disorder makes the children unable to metabolize phenylalanine properly and causing a buildup that can be so disastrous as to cause mental retardation (Spatial, 1). Acute phenyl=higher blood…

responsible for creating the enzyme phenylalanine hydroxylase. This enzyme breaks down the amino acid phenylalanine into tyrosine for the body. This mutation causes the PAH gene to not break down the phenylalanine and because so, dangerous and toxic levels of phenylalanine can build up in the blood, brain, and other organs and tissues. Without being able to digest phenylalanine, the amino acid will build up in the body and cause serious deficits. Phenylalanine is found in all proteins so people…

(PKU) is a disorder that can be passed down from generation to generation. It is caused by a deficient hepatic phenylalanine hydroxylase (PAH), which is an enzyme in the liver that catalyzes the conversion of phenylalanine to tyrosine, using the coenzyme, tetrahydrobiopterin (BH4). One treatment for PKU would be to have a restricted diet because PKU does not allow for the process of phenylalanine, which is a protein found in many foods (Scala et al 2015). With the help of BH4, patients are able…

Phenylketonuria (PKU) is a genetic disorder caused by a defect in the gene that helps create the enzyme phenylalanine hydroxylase. This enzyme helps to breakdown the amino acid phenylalanine; without this enzyme the levels of phenylketonuria (PKU) increases, this causes serious cognitive disabilities, hyperactivity, seizure, and abnormal small head (microcephaly) in infants, and small risk of brain damage.1 Phenylketonuria can affect pregnant women, babies, children and adults. Therefore, people…