Pharmacokinetics

Pathophysiology Tinea pedis, or athlete’s foot, is the term used for a dermatophyte infection of the sole of the foot and interdigital spaces (Porth, 2015). This infection is most commonly caused by Trichophyton rubrum, initially endemic to a small region of Southeast Asia. Dermatophytes are fungi that require keratin for growth. The fungus that causes tinea pedis falls under this umbrella. Other causes of tinea pedis include: Trichophyton mentagrophytes and Epidermophyton floccosum. The…

health professionals. chatswood: Elsevier. NCBI. (2014, april 25). Retrieved from pubmed.com: http://www.ncbi.nlm.nih.gov/pubmed/9190321 News Medical. (2015, march 17). Retrieved from News Medical: http://www.news-medical.net/health/Morphine-Pharmacokinetics Tiziani, A. (2010). Harvard 's Nursing Guide to Drugs. chatswood:…

The human immunodeficiency virus or HIV is a virus that unlike many other viruses the body can not fight it off, once contaminated with the virus the person must live with the human immunodeficiency virus for the rest of their life. What HIV does is it kills off CD4 Cells or T Cells which are white blood cells that the immune system develops in order to helps the body fight off diseases, infections and other viruses. If the HIV virus is not treated, with time the virus kills so many T Cells…

3A.2.10 Robustness A method is robust if it is unaffected by small changes in operating conditions. To evaluate the robustness of developed analytical method few parameters were deliberately changed. The parameters included analysis at different temperatures viz. 250C and 300C, at 0.8 and 1.0 mL/min flow rate, using C18 columns from different manufacturers one from Qualisil BDS, USA (4.6 x 250 mm x5µ) and the other from LC-GC, India (4.6 x 250mm x5µ). Each of the three selected factors were…

The pharmacy profession undergone massive changes in the past few years with a number of countries encouraging more patient-oriented clinical roles and having pharmacists incorporated alongside doctors, nurses and other healthcare professionals into a multidisciplinary team. Certain countries such as the United Kingdom, the United States, Canada, Australia and New Zealand are expecting their pharmacists to be vastly available to patients in the community in order to provide counseling about…

sprinkle the pieces onto food to ease the swallow of a person with dysphagia. While this method works for some drugs, other drugs can cause harm when they are digested after being crushed into pieces. Crushing up certain drugs can interfere with the pharmacokinetics and pharmacodynamics of the drugs; when the absorption of the drug is affected this can affect the body’s reaction to the drug (Griffith, 2016). For example, enteric-coated drugs, sustained release drugs, and sublingual drugs are…

Sophomore Persuasive 12/08/17 Animal Experimentation Formal Outline I. Introduction "...even if considerable congruence were shown between an animal model and its corresponding human disease, interspecies differences in physiology, behavior, pharmacokinetics, and genetics would significantly limit the reliability of animal studies, even after a substantial investment to improve such studies" (Akhtar 411). Animal experimentation is one of the oldest practices still used in the status quo.…

I am a strong believer that life is a gift and it is the greatest teacher to oneself and nothing can be a better way to use it productively than the path of science. My journey started from all the way from undergraduate has been a mixture of learning from various interdisciplinary fields. The skills of experimenting and practice are the two elements of my faith which built the foundations of what I still cherish are the long hours in the laboratory of my mentor Professor P Rajeswara Rao. The…

How does the human genome sequence and more specifically the individual genes affect our response to medicine? Before this question can be answered you must know understand what the genome and the gene is exactly and what it does. A gene is the basic physical and fundamental unit of heredity, made up of deoxyribonucleic acid that carries a certain set of genetic instructions. The human genome is estimated to have up to 25,000 genes, varying in size with some carrying a few hundred DNA bases,…

the bioanalytical determination of biopharmaceuticals.1 In pharmaceutical R & D, it takes a year to develop a new marketing drug identified from thousands of new compounds. The drug discovery is divided into early and late phase, during which pharmacokinetics study or bioanalysis of a drug is done. Once, the bioanalysis of a drug is done, the next step is the drug development in which, a drug is studied for its toxicokinetics during its pre-clinical and clinical trials. After all these trials…