Pharmacokinetics

photodetector devices2. Once attached on specific proteins, quantum dots become an effective tool in bioluminescence imaging3. The migration of target cell or protein can be tracked, providing valuable information in embryology, physiology and pharmacokinetics field3. A number of biomedical researches have applied this technology, such as cancer study and Parkinson’s diseases study. Large amount of information can be obtained through…

simple. It’s composed of porcine pancreatic glands: lipase, amylase and protease. The capsule is designed to dissolve in the slightly more basic pH of the duodenum rather than the stomach so that they can break down fats, protein and starches.5 Pharmacokinetics: Absorption It is not significantly absorbed in the…

As strange as it may sound, my first encounter with pharmacy happened even before I learned how to speak. In Vietnam, there is this spiritual First Birthday ceremony by which all one-year-olds must pick an item such as a stethoscope or a money note from a tray of twelve, each of which is thought to link to the baby’s future career and will “forever seal their fate”, in the words of my grandmother. According to my mother, when facing with the tray, I immediately chose a drug box! Years later, I…

Nano Precision Medical is an early-stage start-up company located in Emeryville, CA. Its founders are Adam Mendelsohn, Kayte Fischer, and Lily Peng. Their entrepreneurial story began in December 2007 while they were part of a Joint Graduate Group in Bioengineering under the supervision of Professor Tejal Desai at the University of California, San Francisco (UCSF). Adam Mendelsohn, Ph.D. was working on “describing new treatment options for Type 1 diabetes through the immuno-isolated…

Soaring price of generic drugs: Depriving consumers from better healthcare Generic drugs prices are rising exponentially with every passing year. Generic drugs are regarded as a boon to mankind not only because they are comparable to their brand counterparts in terms of quality, safety and efficacy but also because they are affordable by all the people irrespective of their financial class. A survey revealed that generic drugs have saved US patient’s 1.3 trillion dollar in past decade. But with…

Acute Myeloid Leukemia (AML) is generally addressed by a chemotherapy regimen, however, this method of treatment is highly nonspecific and a relapse of the disease occurs in a majority of patients. Due to the nonspecific nature of the chemotherapy drug, it is hypothesized that chemotherapy temporarily solves the problem and fails to completely eliminate the the cancer stem cells, which harbor the potential for self-renewal and continuous proliferation. This has lead to the need for a better drug…

OBJECTIVE: To deliver lornoxicam into systemic circulation by engineering ethosomal gel formulation. RATIONAL OF WORK: Because of their improved pervasion of medication through skin.  lornoxicam is BCS class II medication causes gastric bothering when managed orally  ethosomes are stages for the conveyance of vast and differing gathering of medications.  due to their generally safe profile.  better understanding agreeability can be utilized as a part of the manifestation of gel,…

HC, Meier PG, et al. St John’s Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clinical Pharmacology and Therapeutics. 2000;68(6):598–604. 9. Johne A, Brockmöller J, Bauer S, Maurer A, Langheinrich M, Roots I. Pharmacokinetic interaction of digoxin with an herbal extract from St John’s wort (Hypericum perforatum). Clinical Pharmacology and Therapeutics. 1999;66(4):338–45. 10. Müller WE, Singer A, Wonneman M. Hyperforin--antidepressant activity by a novel…

INTRODUCTION Oral Controlled Release Drug Delivery Systems1, 2: Oral controlled release drug delivery is a drug delivery system that provides*give the continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specific region within the GI tract for either local or systemic action. All the pharmaceutical products formulated for systemic delivery via*throw…

Pharmacokinetics: How the body acts on the drug a) What route was chosen and why. Jack was prescribed 47.5mg of Metoprolol succinate and this is given in a single oral dose. The tablet is circular and film coated and can be halved to make it easier to swallow…