Pancreatic cancer

the relationship pancreatic cancer- PSC can be described by a pathological feedback loop that is not completely understood. Cancer cells stimulate stellate cells to secrete more vascular endothelial growth factor, but stellate cells contribute to the hypoxia of fibrotic tissue by increasing the endostatin production [11]. Although, several studies confirm that stellate cells contribute to tumor growth and metastasis, it is poorly understood the mechanism by with they do it. There is no evidence that the elimination of PSC mitigates the progression of cancer, yet the modulation of these ones might influence it [12]. Overall, it is uncertainty if SC are really partners in crime or some sort of double agent that also regulates spread of oncogene-initiated epithelium. My goal is to use a mechanistic approach to explore the apparatus of action of pancreatic stellate cells and the influence of its activation in their microenvironment and cancer cells. Consequently, this knowledge can provide a practical way to find novel therapeutic targets and improve patient’s quality of…

Cell Signalling and Disease Project: Pancreatic Cancer Symptoms of pancreatic cancer are rarely visible until the disease reaches an advanced stage, which contributes to the low survival rate (six percent). When symptoms are present, they include body pain (specifically in the torso or middle back), nausea, fatigue, blood clotting, dark urine, weight loss, and yellowing on the skin and eyes. This disease very rarely afflicts people under the age of forty-five, although it is possible. Although…

Pancreatic cancer has claimed the lives of many people, including a number of popular individuals like businessman Steve Jobs of Apple and actor Patrick Swayze of the movies Dirty Dancing and Ghost. Their cancers were already at an advanced stage when they were diagnosed. Pancreatic cancers spread stealthily in the body; they do not show early warning signs particular to the condition. What is Pancreas Cancer? The pancreas is an organ in the body located between the stomach and the backbone.…

Pancreatic cancer is the tenth most common malignancy, and is the fourth leading cause of cancer related mortality in both women and men in the western world. It is predicted that by year 2020 pancreatic cancer will surpass colon and liver cancer related mortality, making pancreatic cancer the second leading cause of cancer related death, placing it just behind lung cancer (8)(9). The American Cancer Society estimates 48,960 new cases of pancreatic cancer for year 2015, and is estimated that…

In just this year to come, more than 46,420 people in the U.S. will be diagnosed with pancreatic cancer. Out of them, about 39,590 people will die from the disease – that’s 85%. While all types of cancer may be fatal, pancreatic cancer is ranked number 4 on the list of deadliest cancers ("Pancreatic Cancer Facts"). Whether the cancer was acquired genetically or due to a carcinogen (a substance capable of causing cancer in living tissue), it will go on to affect the cancer patient and everyone in…

Pancreatic Cancer In the U.S an estimated 46,420 will be diagnosed with pancreatic cancer and over 39,590 will die from this disease. For stage IA there’s only a 14% chance of survival and for stage IV there’s only a 1% chance. Not many people want to know these statistics, because they might lose hope if they are fighting the disease; for those that would like to gain an understanding it should be made clear. Knowing this, it’s best to learn the facts of how this cancer can be prevented…

Pancreatic cancer Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems. Cancer is not just one disease but many diseases. Cancer is a variety of diseases that are characterized by uncontrolled cell growth and possible destruction of surrounding normal cells. The International Agency for Research on Cancer has classified some 60 substances and…

People who are at risk should get tested earlier. Diagnosis rates for pancreatic cancer are not very high. Most people at risk do not get tested because they think they do not need to. Since the risk of getting pancreatic cancer is relatively small, people do not get tested because they think that they will not get it. For example, people who have close relatives who have had pancreatic cancer are at higher risk. “If you have two or more first-degree relatives who have had pancreatic cancer, a…

Pancreatic Cancer Pancreatic cancer is an abnormal growth of cells (tumor) in the pancreas that is cancerous (malignant). The pancreas is a gland located in the abdomen, between the stomach and the spine. The pancreas makes hormones that help the body use and store energy that comes from food. The pancreas also makes pancreatic juices that help digest food. Pancreatic cancer can spread (metastasize) to other parts of the body. The abdominal lymph nodes are the first place that may be affected…

by the institutional review board (IRB) of the University of Texas MD Anderson Cancer Center. The clinical and survival data of the study population (130 pancreatic cancer patients) was identified from a database that is prospectively maintained by the Department of Surgical Oncology at MD Anderson Cancer Center. A waiver of consent was granted for the use of their specimen information for research. To identify new molecular markers for early diagnosis of pancreatic cancer and predictive…