Paclitaxel

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  • Risk Of Infection From Swimming With Contact Lens On

    Eligible patients were randomly assigned to receive either gefitinib (at a dose of 250 mg per day orally) or standard chemotherapy. The standard chemotherapy is paclitaxel (at a dose of 200 mg per square meter of body-surface area, given intravenously over a 3-hour period) and carboplatin (at a dose equivalent to an area under the concentration–time curve [AUC] of 6, given intravenously over a 1-hour period), both…

    Words: 1087 - Pages: 5
  • Essay On Coronary Artery Disease

    Coronary artery disease continues to maintain its status as the leading cause of morbidity and mortality in the United States. It is a high priority of clinicians not only to manage the acute symptoms of coronary artery disease, but also to prevent future major adverse cardiac events, such as acute myocardial infarction and cardiac death. Percutaneous coronary intervention is a nonsurgical procedure to treat atherosclerosis within the heart’s vessels (cite). Percutaneous coronary intervention, a…

    Words: 1256 - Pages: 6
  • Essay On Intravenous Infusion

    grandmother, who passed away from ovarian cancer never dreamed. Ovarian cancer causes more deaths than any other gynecologic cancer in the United States. “FDA approved bevacizumab solution for intravenous infusion (Avastin) in combination with paclitaxel, pegylated liposomal doxorubicin, or topotecan, for treatment of patients with platinum-resistant recurrent epithelian ovarian, fallopian tube, or primary peritoneal cancer”,…

    Words: 774 - Pages: 4
  • Native American Herbal Medicine

    This paper will examine the medicine and healing techniques of the Native American people and the historical context behind the use of these medicines. It will attempt to uncover the healing properties of traditional herbal medicines as well as the spiritual power to heal human pathologies. Specifically the paper will examine the healing properties of natural remedies including nutritional and spiritual practices used by the indigenous peoples of North America and how those practices might…

    Words: 1009 - Pages: 5
  • Liposomes Lab Report

    drugs have been developed. For instance, active loading of the amphipathic weak acidic or basic drugs in empty liposomes can be used to increase the encapsulation efficiency. However, active loading is not suitable for hydrophobic drugs such as paclitaxel for which encapsulation efficiency is < 3mole% mainly due to the low affinity of drug for the lipid bilayers.91, 95-97 4. Lysosomal degradation: One of the major limitations of active targeting using ligand-directed immunoliposomes has been…

    Words: 1052 - Pages: 5
  • Drug Encapsulation Essay

    96 Aqueous One Solution Cell Proliferation Assay Kit (Promega of USA). All cells were plated overnight in 96 well plates with a density of 5,000 cells per well in 100 µL appropriate growth media overnight in a 96 well plate. The cytotoxic drugs (Paclitaxel, ACIN, AMIN), ACIN/COS NPs, AMIN /COS NPs, ACIN/COS-SMCCGGRGDSK NPs, and AMIN/COS-SMCC-GGRGDSK NPs were added to the wells at drug concentration equivalent to 30 µM for the free drug or the drug loaded NPs. The cells were incubated at 37 oC…

    Words: 975 - Pages: 4
  • Cisplatin Research Paper

    respectively. There will probably be continued and extended use of platin-containing regimens with the new generation of molecularly targeted therapies, as exemplified by the recent approval of bevacizumab in combination with carboplatin and paclitaxel in patients with lung cancer; breast cancer provides additional possibilities. Improved tumour-delivery strategies and co-administration with specific modulators of prevalent platin-resistance mechanisms might also provide future clinical…

    Words: 951 - Pages: 4
  • Erythromycin Case Study Questions And Answers

    1. Describe 3 targets of antibiotics, why each target is unique to the particular bacteria, and under what circumstance the bacteria could be resistant to that particular drug. (5 pts) As the name implies 50s subunit protein synthesis inhibitors such as erythromycin inhibit protein synthesis by binding to the 50S subunit of the 23S rRNA molecule of the bacterial ribosome. This ultimately acts to block the exit of the growing peptide chain. It should be noted that gram+ bacteria more…

    Words: 1362 - Pages: 6
  • Dex-Ibuprofen Research Paper

    ABSTRACT Dex-Ibuprofen–polyethylene glycol (PEG) conjugates (PEG-dex-Ibu) were organized and their prospective as a prolonged release method was investigated. PEG-Dex-Ibuprofen conjugates were synthesized as of Ibuprofen and PEG with 4000 Da molecular weights by esterification in the incidence of DCC and DMAP. The PEG-dex-Ibu conjugates were characterized by FT-IR, 1H NMR, and DSC analysis. The solubility revise in aqueous system showed an improvement within the solubility of conjugates. The…

    Words: 1362 - Pages: 6
  • Anton Cancer: A Case Study

    CHAPTER 1 INTRODUCTION Since time immemorial microorganisms have played a significant role in the life of mankind owing to the production of the myriad enzymes and secondary compounds that they synthesize (Demain 1981). These micro organism live in a highly diverse environment ranging from hot springs to deep ocean sediments. In the hyper diverse environment where one can find a specialized and unique biological niche is the intracellular space between cells of higher plants acts as suite and…

    Words: 3418 - Pages: 14
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