Osteoclast

remodeling is essentially a lifelong process. The mature bone tissue is removed and replaced the new bone tissue. This promotes healthy bones and can also reshape the bones from injuries like fractures. Osteoblasts secrete new bone tissue while osteoclasts break down the old bone tissues. The body signals the correct amount of growth through parathyroid and growth hormones as well as vitamin D, steroids, and calcitonin. 2. Compare and contrast bone growth and remodeling. • Bone growth is the…

Osteopetrosis is a clinical syndrome characterized by the failure of osteoclasts to resorb bone. As a consequence, bone modeling and remodeling are impaired. The defect in bone turnover characteristically results in skeletal fragility despite increased bone mass, and it may also cause hematopoietic insufficiency, disturbed tooth eruption, nerve entrapment syndromes, and growth impairment. Researchers have described several major types of osteopetrosis, which are usually distinguished by their…

a rare genetic bone disorder that causes bones of individuals to be abnormally dense and has 1.7 occurrences per 1 million births (hindawi paper). The abnormal mutation of the gene that codes the enzyme cathepsin-K causes a disruption in normal osteoclast production. This disease occurs more commonly in male children than female children at a 2:1 ration (hindawi), but other factors such as age and race seem to show minimal differences. Many of the symptoms of Pycnodysostosis are associated with…

SUMMARY OF CASE STUDY Bill, a 34 year old male, arrived at the doctor’s office experiencing pain in his right hip. Prior to this, Bill maintains an overall healthy lifestyle which includes exercising and activities such as; swimming, water skiing and scuba diving. Bill reports he has had no trauma to his hip. On this visit an analgesic and muscle relaxant were both prescribed to the patient and he was sent home. After three weeks of no improvement Bill has returned to the doctor’s office and has…

I Blame the Hormones By: Taylor Aubin Organs and tissues that make up the endocrine system are the hypothalamus, pituitary gland, thyroid gland, thymus, suprarenal glands, pineal gland, parathyroid glands, heart, kidneys, adipose tissue, digestive tract, pancreas, and gonads. The effects of the endocrine system are vast and impact almost every organ and cell of the body. This system produces hormones that help maintain homeostasis through the regulation of metabolism, growth, tissue function,…

cartilaginous tissue occurs, and continues throughout their life. Ossification is the gradual replacement of cartilage and its intercellular substance by bone cells that are immature, and calcium deposits. • What are the roles of Osteoclasts and bone formation? Osteoclasts are large cells that have the function of reabsorbing bony tissue. They digest bone tissue from the inner sides of bones, which enlarges the…

Osteoclasts and osteoblasts are responsible for breaking down bone and replacing resorbed bone respectively (Seriolo et al., 2013). Natural aging results in less bone formation from osteoblasts causing more bone resorption and therefore negatively impacting…

parathyroid glands that are located in the neck are responsible for producing the parathyroid hormone that helps regulate the levels of calcium, phosphorous, and vitamin D throughout the body. Abundant amounts of the parathyroid hormone will cause osteoclasts to become hyperactive and weaken the bone by breaking it down to allow calcium to leave the bone and fuse into the bloodstream. Without the necessary minerals, the bone will not function properly so tissue will form to replace the bone’s…

either Alendronate or Calcitonin which are both drugs that stop the loss of bone, help rebuild the bone and help lessen the risk of a fracture significantly. Alendronate protects the bones from the osteoclasts while calcitonin also helps protect the bone by slowing down the osteoclasts cells. Osteoclasts cells destroy old bone tissue. Having a healthy diet that is high in both calcium and vitamin D while working out or exercising are preventions and also treatments of osteoporosis. Eating a lot…

sometimes just disappear which means the skeletal system is losing bone after bone. In your bone you have 2 different bone structures which are cortical bones and spongy bones, you also have cells in your bone and the cells are called osteoclasts. When osteoclasts are put in motion they are the substance that absorbs the calcium from your bones which makes them tin out. The falling and the minerals being sucked out of the bone makes the bone weak, when the bone gets weak they start to fade,…