are two important glands that work to keep the calcium levels within the blood balanced: the thyroid and the parathyroid glands. When the body has low blood calcium levels the parathyroid gland will act and secret PTH which will activate osteoclasts. The osteoclasts will help break down the bone and release the calcium from the bones to the blood stream. While it will also activate vitamin D which will help increase the absorption of calcium from the kidneys and intestines. Therefore, the body…
bone cell that is best suited for this task is an osteoclast. The osteoclast is a bone absorbing tissue that helps break down unwanted tissue during growth and regeneration. 9. The bone matrix is composed of both organic and inorganic substances. The organic substances include collagen, proteoglycans, matrix proteins, cytokines, and growth factors. The inorganic substance includes calcium hydroxyapatite and osteocalcium phosphate. The osteoclasts are involved in the breakdown and reabsorption…
stages to repair. 1.Hemata formation - due to fractured bone, the blood vessels are also ruptured and caused hematoma formation and inflammation. This allow clotting process and bone cells die at the broken ends. These dead bone cells are remove by osteoclasts. 2.Bone generation - phagocytic cells clear away the dead cells and capillaries grow again. Fibroblast produce collagen fibers that connect the broken bone ends, while osteoblasts start to form spongy bone, these two enter the area. The…
Metastatic bone disease is explained by Mercadante (1997) as disease that develops when there is abnormal metabolism within the bone with increased osteoclast activity. Patients with bone metastasis often present with pain, they are also at an increased risk of hypercalcaemia, fractures and in some cases metastatic spinal cord compression, all of which compromise the patient's functional status, quality of life, and survival. Clinicians should utilise the World Health Organization analgesic…
indicates that the bone has completed its growth in length. Cartilage cells are produced by mitosis and are destroyed and also replaced by bone on diaphyseal side of the plate. Zone of calcified cartilage contains mostly dead chondrocytes invaded by osteoclasts and osteoblasts, zone of resting cartilage firmly joins the epiphyseal plate to the epiphysis, zone of proliferating cartilage is where chondrocytes divide to replace those at the diaphyseal side of the epiphyseal plate and zone of…
Osteoporosis Osteoporosis is a bone disease that affects the bone mass making bone become weak and brittle. This disease does affects a large majority of the population. According to the National Osteoporosis Foundation “a total of 54 million U.S adults age 50 and older are affected by osteoporosis.” There are many risk factors that are tied into this disease which will later be discussed. With knowledge of this topic maybe research will help prevent some of the risk that go with osteoporosis…
INTRODUCTION:. Orthodontic treatment are potentially unstable although a number of factors can be cited as influencing long term-result. It called relapse orthodontics. Relapse Orthodontic is the return, following correction, any change from the final tooth position at the end of treatment relapse, could be a return to the original teeth position, caused by periodontal,occlusal,soft tissue factor and growth. Orthodontic relapse is a complex problem. 1,2 Studies have shown that stability and…
The human body has two hundred six bones that make up around fifteen percent of all body weight. They are vital for a body’s regular activities, so it can be very devastating when the bone is harmed from disease or injury. Many have suggested some factors that contribute to the harming of bone, but one of the most prevalent ones is caffeine. The purpose of this paper is to describe the anatomy of the human bone, discuss the health of bones, and show caffeine’s effect on the calcium in bones…
Osteoporosis is very common in the world we live in today. About 54 million Americans are diagnosed with this disease. Osteoporosis is a bone disease that cutbacks bone mass. The bones become very brittle and frail and are unable to support your weight and usually fracture. The bones that are most likely to fracture are your hips, spine, wrist, shoulder and hip. The bones could become so weak that even if you were to cough or bend over they would fracture. As you grow your bones make new bone…
Some of these cells include osteoclasts, renal intercalated cells, and epididymal clear cells. Osteoclasts are large multinucleate cells that are involved in bone formation and also the remodeling of bone. Renal intercalated cells participate in acid-base homeostasis. Epididymal clear cells are part of the epididymis…