Organic reaction

conversion of a primary alcohol to 1-bromobutance with the Sn2 mechanism using sodium bromide and then to characterize the compound with two different alkyl halide tests. DISCUSSION AND CONCLUSION Nucleophilic aliphatic substitution involves chemical reactions where a neutral molecule or an anion called a nucleophile substitutes a leaving group by attacking an electrophilic, Lewis acidic carbon atom. Leaving groups are molecular compounds that are departed and replaced by the nucleophile. This…

A Friedal-Craft reaction was performed to synthesize 1,4-di-t-butyl-2,5-dimethoxy-benzene from p-dimethoxybenzene and t-butyl alcohol. The product of the reaction was filtered using a Hirsch funnel, before recrystallizing and filtering a second time. The recorded mass of the product was .08g and the melting point was 47-52.7 °C. Introduction1 This experiment was designed to practice working with electrophilic aromatic substitution reactions. Specifically, a Friedel-Craft reaction was used to…

These highly reactive MOBs and MPBs intermediates undergoes numerous transformations such as cycloaddition reactions (ii) nucleophilic, electrophilic, and radical addition reactions, and (iii) photochemical reactions17. On account of their unique reactive features, rapid and easy generation they grabbed the attention of synthetic organic chemists. Synthesis of biaryl18,19 have received much attention in recent years because of their frequent occurrence in many natural…

The propylene glycol is considered to be one of the common organic compounds which can be used in many life applications. It can be used in antifreeze, pharmaceuticals and many applications as well. It can be produced by hydrolysis of propylene oxide that is accelerated by the catalysis of base or acid. The goal of the experiment is to produce propylene glycol using water and propylene glycol as a reactant to synthesis propylene glycol. The purpose of doing this experiment is to converge and…

In this experiment, a Wittig reaction was performed in order to synthesize a mixtures of (E)- and (Z)-stilbene. Photoisomerization was then performed to isolate (E)-stilbene by transforming (Z)-stilbene into (E)-stilbene. The presence of the products throughout the experiment was monitored by 1H NMR. The final product was then characterized by 1H NMR, IR and its melting point. During synthesize of the product, the appearance of the reaction mixture changed. The main solution…

as the rate of reaction did increase as the concentration and the temperature increased. The concentration, or molarity, of the reactants increased in relation to time in the form M=1.1541e0.0016t. This is an accurate relationship as the volume remains the same as the number of molecules increase, thus the rate would increase exponentially as the molecules collide at a constant growth rate. This is also a reliable model as the R² value is 0.9697. The hypothesis that the reaction would be first…

Scheme 3. Substrate scope of the Mannich reaction of 5 to α-amido sulfone 3. Reactions were performed with 5 (0.1 mmol), 3 (0.12 mmol), KF (0.3 mmol), and (R)-1b (10 mol%) in o-xylene (1.5 mL) at 25 °C. The yield was determined after chromatographic purification, and the ee value was determined by HPLC analysis using a chiral stationary phase. Diastereomeric ratio was determined by 1H NMR. To demonstrate the scalability of the process and the application potential of the resulting chiral Mannich…

Pseudomonas aeruginosa than Saccharomyces cerevisiae. Under this study, after centrigugation of crude extract,the pellets were suspended in a 40 mL of dichloromethane in a separating funnel and shaken vigorously and the allowed surfactant recovered in the organic layer at…

ring which makes it more reactive. On the other hand, if benzoic acid replaced anisole in the experiment, it would act as a deactivating group. Carboxylic acid pulls electrons from the benzene ring acting as a withdrawing group which causes a slower reaction with the increase of stability and decrease in reactivity due to resonance. The electrophile is formed from acetyl chloride once the aluminum trichloride (AlCl3) is added hence, forming the carbocation and the Tetrachloroaluminate (AlCl4…

color signaled the end of the titration. The amount of the oxalic acid in the solution was found to be 8.941%. The redox titration was precise in the quantification of oxalic acid with a standard deviation of 1.327%. Introduction One of the natural organic compounds found in plants is the oxalic acid. It is commonly found in leafy greens, and nuts, as well as in some fruits. Spinach is known to have the highest amount of oxalic acid in vegetables of about 750 mg for every 100 gram serving…