Opioid receptor

Drug addiction is a serious issue that affects many people; the sad reality to a drug addiction is that not everyone is able to get proper help they need to get better. Many times, these drug addictions only escalate into something much more serious like death due to an accidental overdose. In the film, The Panic in Needle Park, the main character Bobby is a heroin addict who lives in an apartment with his new girlfriend named Helen. They live on the West Side of New York and it is officially…

As of late, there has been a drastic increase in deaths due to opioid overdoses, this crisis has spread across our country, and has caused President Trump to publicly come out and describe it as a ‘national health emergency’. Opioid overdoses have destroyed families, careers, and more importantly, it’s taken lives, but Seattle and King County have been taking action on this issue, by creating the nation’s first-ever safe injection site. This is reportedly inspired to be like Vancouver B.C.'s…

Drug addictions is one of the most destructible things a person can do to themselves. Illicit drugs are becoming more popular on the streets and are taking more lives every single day. One very popular drug on the street is heroin. Many people who used heroin started off using marijuana or prescription drugs and switched for a stronger drug. They are unaware of the health risks of this dangerous drug. Heroin is a drug made from poppy plants and is a thick powder. It is highly addictive and…

Heroin, like most other popular drugs, is used every day. The most common use for heroin is for recreational purposes. Not only can heroin be injected, but it can be sniffed, snorted, or smoked. This drug can be highly addictive which can lead to death. It also causes lots of harm to your body Heroin is dangerous because of the extensive number of users, the makeup of heroin, the short term effects on users, and the long term effects on users. To begin with, there is an extensive number of…

Everyday 91 people die from an overdose in the United States. These deaths are not all from street drugs. Since 1999 prescription related opioid overdoses have resulted in the death of 183,000 people. Many people develop opioid addiction from being prescribed an opioid for common injuries, accidents, or illnesses. Along with opioids, stimulants and depressants are commonly abused and misused and it becoming a growing problem. Prescription drugs are drugs designed to treat a specific illness,…

which plays a role in synaptic plasticity, learning and memory. It has been observed that there is approximately a 90% loss of acetylcholine in the brains of people afflicted with Alzheimer’s disease (Boeree, 2009). The α-7 nicotinic acetylcholine receptors (α7- nAChRs) are highly expressed in the hippocampus (Prickaerts et al., 2011). Hippocampal long-term potentiation (LTP) is the constant increase in the efficiency of synaptic transmission. Research supports the hypothesis that α-7 nAChR…

These receptors are found in the cardiac muscle and their stimulation has a positive inotropic effect (increases the contractility of the heart). It does so without significantly increasing heart rate or affecting peripheral vascular resistance (as it does not activate alpha adrenergic receptors of blood vessels). The result is increased cardiac output via increased stroke volume (Tariq & Aronow, 2015)…

Additionally GLPP-1 receptor agonist treatment has shown reduction in the occurrences of hypoglycemia when chosen as a mode of treatment. Clinical trials were extensively conducted for about 84 weeks. In Comparison with Insulin Glargine, Exenatide QW lowered A1C level significantly…

unfortunately, two thirds of this population are between 12 and 17 years old (Sofuoglu, Sugarman & Carroll, 2010). Marijuana contains an active ingredient, tetrahydrocannabinol (THC) which alters the human central reward pathway by stimulating cannaboid receptors in the place of anandamide, a hormone of the endocannabinoid system, ultimately causing a sense of euphoria, a common attribute of other abused…

My research interests are focused on molecular mechanisms of memory formation during infancy. I’m very interested in exploring how experiences during infancy results in hippocampal long-lasting changes, which influence adult behavior. Traumatic early life experiences can predispose individuals to psychopathologies, including post-traumatic stress disorder (PTSD), borderline personality disorder, addiction, depression and anxiety1-4. Paradoxically, episodic memories formed during infancy are…