Depression is a brain disorder which generate major disability. Its etiology and molecular mechanism is not fully understood. It is a leading cause of disability globally, with lifetime prevalence as high as 20% (Kessler et al., 2005). Depression is multifactorial disorders that differ in symptomology and most possibly in etiology. There are various symptoms of depression include depressed mood, mood swing, loss of pleasure activities (anhedonia), inability to concentrate, lack of energy,…
INTRODUCTION The nervous systems are developed by the proliferation of progenitors in the epithelium, the specification of neurons and glia, the growth and guidance of axons and dendrites, and the development and refinement of electrical and chemical synapses. In the central nervous system (CNS), stem cells reside throughout life in the forebrain, continuing to generate neurons and glia in the subventricular zone (SVZ) surrounding the lateral ventricle and in the dentate gyrus of the…