Nucleoside

Human Immunodeficiency Virus (more commonly known as HIV) is a disease that has been around for over 3 decades, and continues to rise with little to no sign of eradication. The origin of HIV is not certain but there are several theories with the most popular one being that it came from a mutation of a similar virus found in chimpanzees. An estimated 35 million people are living with HIV around the world. Because of this, many scientists are doing research to try to pinpoint the mechanism of its…

Sung Noh 12/11/2014 BSCI 330 Hypermethylation in patients with Myelodysplastic Syndrome Myelodysplastic Syndrome is disease of the bone marrow in which its ability to produce viable blood cells has been compromised through mutation. In healthy bone marrow the Osteocytes that live within produce hematopoietic stem cells that mature to become different components of blood: erythrocytes, neutrophils, monocytes and platelets (Saba et. al, 2007). Osteocytes that have undergone mutations produce a…

Abstract. The theoretical treatment of the equilibrium structure of the derivatives was based on the DFT method using the functional B3LYP with the base 6-311 ++ G (d, p). To distinguish the molecular electrostatic potential surface (MESP), we used the principle of HSAB (Hard Soft Acid and Base), in order to have the centers of activity of a molecule and the effects of substitution on the systems of pyrazolooxazine. These have anti-inflammatory activities. In our work, we have applied methods of…

Chemotherapy: Cancers Poison Treatment If a doctor walked up to you and said: I am going to treat what is making you sick with “poison” you would think they are crazy! Chemotherapy, a treatment for cancer, is a poison called nitrogen mustard (mustard gas) used during World War II. Paul Ehrlich the father of chemotherapy found that people exposed to the gas had lower White Blood Cell counts than people exposed to the poison (Tharu, 2014, paras. 3). This was the birth of chemotherapy as a therapy…

Introduction Information processing is crucial in all fields of science. In molecular biology, the central dogma, first devised by Francis Crick, is a classical backbone of living cells to essentially perform the processes from cell division to death through the DNA, RNA, and protein information ways. More specifically, the central dogma defines the transfer of sequence information during DNA replication, transcription into RNA, and translation into amino-acid chains forming proteins. It also…

Daniel Huang Chapter 9 1. Mutations can be very negative in that it can cause cancer in somatic cells. However it is important to note that mutations will also lead to variability which is beneficial to us. Mutations in intergenic DNA affects regulations of protein products which is actually less detrimental than mutations in exons which code for the proteins. 2. Transition is the error that causes the base to change from a purine to purine or pyrimidine to pyrimidine. Transverses are base…

Assignment 1: Metabolism Gone Wrong: Galactosemia Course: Biochem 3D03 TA: Rabia Mateen Name: Kei Cheng Mak ID: 3122260 Date: October 15th, 2014 Introduction Metabolism consists of biochemical reactions catalyzing the conversion of complex macronutrients into usable energy by various enzymes. Energy in food is extracted from three macronutrients - carbohydrate, protein and fat. As food passes through the digestive tract, various enzymes and chemicals in the body break food particles into…

Eradication of HIV There are many ways that HIV is transmitted but if the risk factors were taken out would there be as many individuals affected by this disease? If there was an immunization to protect the CD4 cells would AIDS be a syndrome anymore? Acquired immunodeficiency syndrome is not possible without the human immunodeficiency virus which is the driving force behind scientists collaborating worldwide in ending and preventing this pandemic. Etiology “The primary etiologic agent of…

1.Write about a man-made or natural issue (RESEARCH PAPER-→ I chose GMOs 2. 8-12 pages in length (apparently less than 8 is fine, though) 3. Must use citation (whatever format you like, but MLA or APA are easiest) 4. Must use reputable sources (i.e. do NOT use Wikipedia, Buzzfeed, etc) • Format : • Intro : 3 parts 1. what ? what r u writing about ? whats the subject? from general information narrowed down to thesis (1 or 2 paragraph ) 2. why ? why have chosen this topic ? from all options…

INTRODUCTION Oral Controlled Release Drug Delivery Systems1, 2: Oral controlled release drug delivery is a drug delivery system that provides*give the continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specific region within the GI tract for either local or systemic action. All the pharmaceutical products formulated for systemic delivery via*throw…