Noncoding DNA

BIRTH DEFECTS (AMELIA) Q: What is it? A: To start off with, Amelia (from Greek ἀ- "lack of" plus μέλος (plural: μέλεα or μέλη) "limb") is the birth defect of missing a limb or more. It can also be a form of some sort of shrunken limb. There are other names for this disease if there are one, two, three, or more limbs missing. For an example tetra-Amelia is the missing of all four limbs. Q: What could the cause of this be? A: The absence of an arm or leg in Amelia happens as a result of the…

What do Channing Tatum, Dwain Johnson and Will Smith have in common? They like many other famous actors have...baldness. Men are usually known for their shining dome which stand for their intelligence and maturity but no matter how posh and formal they look they still desire their luxuriant hair. Scientists have long wondered why men lose their hair and how it can be restored. Did you know there are approximately 100,000-150,000 pieces of hair growing out of your scalp. Scientists have…

Elucidating the role of Heat shock proteins in poly glutamine (Poly Q) model in Dictyostelium discoideum . Introduction : Expansion of CAG trinucleotide repeats encoding poly glutamine (poly Q) tract in other wise unrelated proteins are responsible to atleast nine diseases . These diseases include Huntington’s disease (HD), spinobulbar muscular atrophy, dentatorubral pallidoluysian atrophy, and spinocerebellar ataxia (SCA) types 1, 2, 3, 6, 7, and 17.(1) Clinical features include ataxia and…

Case study of X-ray imaging with grating interferometer on pearls Abstract- With the increase of fraudulent conduct in the field of jewellery there has been increase in the demand for inspection to identify the purity of the product. In this case study X-Ray Radiography is used to identify natural pearls and artificially cultured pearls. In order to understand the internal structure a personalized grating interferometer and inspection has been performed to obtain measurements. The computed…

Genetics Testing Introduction to Genetic Testing Genetic testing, also known as DNA testing, is the process of using medical tests used to look at one’s genes, inherited from one’s parents. These tests ranges from identifying a child’s biological parents, to ascertaining if there are any risks of having cancer or diseases. Results of genetic testing may help access on how severe a disease might be and find the best solution to diagnose it. It will also help determine the chances of developing…

The question of “designer babies” is one that is fairly recent and controversy of the topic starts from the very definition of the term. When one is presented with the term “designer babies”, Most people imagine a genetically engineered being who is less human and more technology. This false stigma mainly comes from the negative reputation of Genetically modified species such as food or animals. However, the reality is quite different, it can be argued that even choosing a fertilised cell as an…

K. Russell, D. L. Swerdlow and K. Tonat (2001). Botulinum toxin as a biological weapon: medical and public health management. The Journal of the American Medical Association285: 1059-1070. Bhambhani, A. and C. V. Kumar (2006). Protein/DNA/inorganic materials: DNA binding to layered α-Zirconium phosphate enhances bound protein structure and activity. Advanced Materials18: 939-942. Bhambhani, A. and C. V. Kumar (2008). Enzyme-inorganic nanoporous materials: differential scanning calorimetric…

Cream may have the potential for use as a probiotic carrier because it provides an excellent environment for probiotic bacteria, with the added advantage of having nutritional value.Fatty Acids composition in fermented synbiotic cream, containing one of the two probiotic bacteria ( Lactobacillus acidophilus, Lactobacillus casei ) and inulin (0,1.5, 3%) was evaluated during 30 days for the the15-day interval at 4±1 °C. All chemical characterization were affected by the probiotic bacteria strain…

Aspergillus nidulans: One of the lesser known pathogen of the aspergilli group, A. nidulans is a model filamentous fungus widely used for studying eukaryotic cell biology (Galagan et al., 2005). A. nidulans possesses a phospholipid-hydrolyzing novel cPLA2 protein, PlaA, which shows maximum similarity to mammalian-type cPLA2 proteins (α, β, γ) (Hong et al., 2005). Like the three isoforms of human cPLA2 proteins, A. nidulans PlaA also consists of two separate catalytic domainsA and B, and…

Aim: To understand cell control mechanism of a model genetic terminator system and to develop potential termination strategies through computational modelling . Motivation: The aim of IGEM- IISER Pune team is to develop a rapid, cost effective, sensitive and portable device for detection of tuberculosis. We adopt a three component tuberculosis diagnosing device consisting of 1 Hijacking Module which would take over cell cycle control inducing rapid replication 2 Detection…