Nitric oxide

Acid rain is a rain that is more acidic (has more hydrogen ions) compared to normal rain and it has serious negative effects to nature and people. It is a mixture of wet and dry depositon that contain high amounts of nitric and sulfuric acids (see Figure 1). These gases come from electric generation, factories, forest fires, burning fossil fuels and acid rain forms when these gases react with water, oxygen and air. Wet deposition happens when acid chemicals fall to the ground in a rain or snow…

Introduction Doxorubicin, an anthracycline antibiotic, is commonly used as an effective antineoplastic agent, in the treatment of various of malignancies, including leukemia, lymphoma, and solid tumors. Unfortunately, the clinical use of this drug is limited by cumulative dose-dependent cardiotoxicity, which may cause irreversible and severe effect of cardiomyopathy [1] The specific mechanisms of doxorubicin (DOX) induced cardiotoxicity are complex and although decades of research on this drug,…

treatment regimens are widely studied but there are many challenges. One potential cancer treatment strategy is to induce apoptosis in cancer tissues by the modulation of nitric oxide production . Nitric oxide is a reactive, gaseous molecule formed from the catalytic oxidation of L-arginine to L-citrulline by the nitric oxide synthase (NOS). It has been shown to be associated with the development and progression of cancer by mediating tumour angiogenesis and metastasis3. Hence, inhibiting…

the metabolism of hydroxyurea there is a huge amount of nitric oxide where produced and lead to the stimulation of heme iron containing enzyme, soluble guanylate cyclase, and as a result of this reaction a fetal hemoglobin will produced (Platt, 2008). Therefore, hydroxyurea overcome the bad effects of sickle hemoglobin (HbS), which causes a damage of the cell membrane by different ways leads to hemolysis and the loss of endogenous nitric oxide, on red blood cells (Platt, 2008). Hydroxyurea had…

ACTH-1-39: Product Description ACTH 1-39 is a synthetic polypeptide hormone that consists of 39 amino acids. ACTH 1-39 is commonly referred to as Adrenocorticotropic hormone, corticotrophin, or ACTH. The molecular formula for ACTH 1-39 is C207H308N56O58S1 and a molecular mass of 4541.11 kilo Daltons. The structure of ACTH 1-39 corresponds to the full-length structure of ACTH. The natural Adrenocorticotropic hormone (ACTH) is naturally synthesized by the anterior pituitary gland and its release…

flow. Vascular endothelial cells assist with cardiovascular regulation by producing a number of vasoactive agents. Endothelial dysfunction and a decreases in nitric oxide production are found in hypertension but are more than likely a consequence rather than a cause. Although antihypertensive therapy can restore production of nitric oxide it cannot restore all endothelial function. The sympathetic nervous system is involved in the regulation of blood pressure since it causes arteriolar…

acidic properties that are water soluble (mainly sulfur oxide) to the ground. The water cycle itself is not harmed by acid rain, as only the rain part is acidic. The acid is absorbed into the ground and becomes part of the ocean or soil. If the ocean becomes too acidic however, the cycle can become very acidic; as ocean evaporation would potentially contain acidic properties that would rain down again. Oxidation Sulfur dioxide and nitrogen oxides enter the atmosphere via emissions from the…

The benzoin is oxidized with nitric acid to produce benzyl. When benzoin was reacted with nitric acid, an orange color appeared. When was heated the mixture a strong red color appeared in the reflux condenser, which is the visible liberation of nitrogen oxide gases. A total of 0.10 grams of purified benzil was produced from this reaction which contained a detected melting point of 82°C and a 34 % yield. This seemed to be approximately 10 degrees less than the ideal melting point of 94°C, which…

Sickle-Cell Diseases Sickle – cell disease is a kind of disease that infects red blood cells. This disease is inherited disease in which the body is unable to produce normal hemoglobin (1).There are several names for this disease such as sickle cell anemia. This disease spreads in inbreeding because it is a genetic disease. This disease is called sickle cell because the red blood cells under a microscope take a curved or crescent shape like a sickle (tool for harvesting forage).The cells…

The risk of stroke increases if a family member has had a stroke. There are multiple genes that play a role in strokes; some are passed down, while others are mutations. They are Methylenetetrahydrofolate reductase, Apolipoprotein E, Endothelial nitric oxide synthase, Factor V Leiden,…