Nitric oxide

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Agmatine is a well known neurotransmitter. It also works as a neuromodulator in certain processes in the body. It is prepared through the removal of a carboxylic group from L-Arginine. It is naturally stored in the neurons and therefore used in the nervous system whenever required. Agmatine was discovered over 100 years ago in 1910 by Kossel. Its mechanisms of actions on different body functions though have just been discovered. Current research shows that agmatine has the potential for use in…

NOS is responsible for synthesizing nitric oxide (NO) and citrulline from arginine. NO acts as an intracellular and intercellular messenger in low concentrations (important for neuronal differentiation, survival, and plasticity) and a cytotoxic molecule at high concentrations, able to contribute…

Sodium entry is accompanied by water leading to more cell swelling. Additionally, an intracellular Ca2+ overload, together with oxidative stress, activates a set of enzyme capable of producing Nitric Oxide, substance behind astrocytes swelling and destruction of cells structures. NO actions are strictly connected to CNS disorders. Another effect of toxic ammonia is the inhibition of the key enzyme alpha-ketoglutarate-dehydrogenase -which takes…

problem that had potential global proportions. To cite an example, there are lots of scientists and researchers that expressed their concerns regarding the short and long term effects and consequences of acid deposition on the atmosphere. Sulfuric and nitric acids, particularly in large quantities, can burn the ecosystem over a long period of time. Forests, crops, fields and man-made structures are easily affected, being withered and beat up. These cases are very prominent in the Eastern and…

Vasoplegic syndrome (VS) is a well-known form of vasodilatory shock that occurs in up to 44% of patients after cardiac surgery employing cardiopulmonary bypass (CPB)(1). CPB is often associated with a systemic inflammatory response and transient vascular dysfunction that results in profound and persistent vasodilation, leading to a decrease in systemic vascular resistance that grounds severe hypotension refractory to proper fluid resuscitation, and an increased requirement for vasopressors…

CHANGES IN CHEMICAL REACTIONS INTRODUCTION This practical experiment is based is based on the theory of Law of Conservation of Mass stated by Antoine Lavoisier. Antoine Lavoisier was a French nobleman who had a major influence on the history of chemistry and biology. Today he is considered to be the “father of modern chemistry.” In all his experiment he supported the Law of Conservation of Mass. Antoine stated this in his theory, “The law of conservation of mass states that mass can neither be…

Earth, a planet that once was devoid of human, an organism that destroys anything and everything in its path, is currently infected with it. After a prosperous five billion years, Earth is sinking and anything on it will go down too. Everyday, Earth is suffering from an endless beating of human destruction: forests are mowed for land, coals are burned for energy, and oceans are polluted for space. The consequence doesn 't only hurt the Earth itself but everything on it. Such large-scale…

pitchblende, which at the time was thought to be a zinc and iron ore. The mineral was dissolved in nitric acid, and then potassium salt was added to the remaining yellow precipitate. Klaproth concluded that he had discovered a new element when the reaction between the salts and precipitate didn't follow any reactions of known elements. He claimed it to be a new element, but his discovery turned out to be uranium oxide and not pure uranium as he had originally believed it was pure. It took a…

of the loss of copper mass is that not all the Copper on the Aluminum wire of Reaction 5 came off or the reaction was not fully complete. Alternatively, when the irrelevant solutions were discarded into a waste beaker, some of the remaining copper oxide from Reaction 3 did not sink to bottom after having given time to settle. Thus, more mass could have been lost during the decanting…