Systemic sclerosis, is a rare connective tissue disease characterized by vascular and immune dysfunction, leading to fibrosis that can damage multiple organs. 4 The clinical forms rang from limited skin involvement to forms with diffuse skin sclerosis and severe and often progressive internal organ involvement, and occasionally a fulminant course. 1 The affected organs and systems include the skin, lungs, heart, digestive system, kidneys, muscles, joints, and nervous system.2 The pathogenesis…
Introduction Haemostasis is the ability to stop the flow of blood in an event of external injury or a breach in a reasonably sized vessel within minutes without affecting the rest of blood flow in the body. The haemostasis consists of four main processes vascular response, platelet response, Coagulation and Fibrinolysis. But when haemostasis is not stopped and goes overactive or get activated inappropriately activated can cause thrombosis and few other complications. The first three step in…
now. So why take it away. Daylight savings time can increase the sunlight effect on cardiovascular illnesses by lowering blood pressure. “ The journal of Investigative Dermatology tested 24 volunteers and found that the sun increases nitric oxide levels,a chemical linked to blood flow,and results in lowered blood pressure.” That would be great for people who have really bad high blood pressure. They wouldn't even have to pay for…
Hypertension is a heterogeneous disorder that may result either from a specific cause (secondary hypertension) or from an underlying pathophysiologic mechanism of unknown etiology (primary or essential hypertension). Secondary hypertension accounts for fewer than 10% of cases, and most of these are caused by chronic kidney disease or renovascular disease. Other conditions causing secondary hypertension include pheochromocytoma, Cushing’s syndrome, hyperthyroidism, hyperparathyroidism, primary…
airflow such as spirometry test, peak flow, and measures of reversibility bronchodilators, which is all used in clinical practice. Diagnosing asthma is different in every person such as those 5 years and older the doctor can check for levels of nitric oxide using the FeNO test. Children under 5 the treatment should be based on professional judgement until they become older to be able to have clinical tests done. There’s a sequence for testing which is: spirometry, BDR if spirometry is positive,…
Impotence is a kind of sexual condition that involves a partial, total or even an inconsistent inability to achieve or retain abigger harder erection that is certainly satisfactory when it comes to sexual intercourse Do not take Levitraif you are taking any drug containing nitrates in any form. Your doctor should also know if you have pre-existing illnesses such as irregular heartbeat and other forms of cardiovascular disease; blood clots or stroke; Low or high blood pressure levels; kidney or…
the brain (3), lung (4), liver(5) and heart (6). The susceptibility of tissue to ischemia reperfusion injury (IRI) is a major obstacle to both reperfusion after an infarct and successful organ transplantation. Reactive oxygen species (ROS) and nitric oxide (NO) play an important role in mediating cell damage during IRI(7, 8).…
This article provides background information on chronic liver disease and states that it can be caused by many things, including alcohol abuse, chronic viral hepatitis, and metabolic factors. Over time, fibrotic tissue develops and without treatment, causes chronic injury and becomes fibrotic. Fibrosis then impairs the normal oxygenation and vasculature to the liver tissue. The author states that according to a large study, cirrhosis is the fourth leading cause of death due to non-communicable…
muscles can improve cardiac output. Increasing cardiac output naturally improves the delivery of oxygen and nutrients to the different cells and tissues of the body. Additionally, endorphins have been shown to stimulate the synthesis of nitric oxide. Nitric oxide protects the heart by reducing inflammation of the heart’s blood vessels and by preventing the clumping of…
Surfactant therapy is the administration of an artificial surfactant that is placed into the baby’s lungs to help keep the air sacs open, while nitric oxide inhalation is thought to improve oxygenation in MAS after treatment with surfactant due to many infants responding well to the combination. So far, the outlook on MAS is promising being that there is no long-term health effects if/when it…