Nitric oxide

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  • Research Paper On Vascular Anomalies

    relaxation occurs by pumping Ca²⁺ out of the cytoplasm and back into the SR or out of the cell. As the amount of Ca²⁺ decreases, then Ca²⁺ will unbind from calmodulin which would deactivate the MLCK. Relaxation can also occur by inhibiting myosin light chain from undergoing a conformational change and allowing myosin and actin to bind to each other. This inhibition can be attributed to myosin light chain phosphatase which is activated by protein kinase G (PKG) (Forstermann et. al 2006). PKG is activated and phosphorylated by cyclic guanosine monophosphate (cGMP). This is known to be increased by guanylyl cyclase which is stimulated by nitric oxide (NO). In essence, NO prevents the contraction of smooth muscle cells thereby acting as a vasodilator. Nitric Oxide Nitric oxide synthase (NOS) can be subdivided into three different isoforms: endothelial nitric oxide synthase (eNOS), inducible NO synthase (iNOS), and constitutive NO synthase (cNOS) (Forstermann et. al 2006). eNOS, the predominant NOS isoform, is a major player in fighting vascular disease and is responsible for most of the NO produced in tissue (Forstermann et. al 2006). NO and L-citrulline are produced when the functional eNOS oxidizes its substrate L-arginine (Forstermann et. al 2006). Therefore, if NO is increased, then more NO and O₂⁻ can react to form ONOO⁻ which leads to eNOS uncoupling (Forstermann et. al 2006). NOS uncoupling has been found in patients that display endothelial dysfunction (Forstermann et.…

    Words: 1329 - Pages: 6
  • Major Effects Of Air Pollution

    (SO2) and nitrogen oxides (NOx) gases. The combustion of high sulphur content fossil fuels can release harmful toxic gases into the air and therefore pose serious environmental problems. Coal, oil and natural gas are major energy resources available in environment where as fuel combustion processes and power plants are the largest contributor of these gases in the form of flue gas. Since coal and petroleum often contain sulphur compounds, their combustion generates SO2 unless the sulphur…

    Words: 1280 - Pages: 6
  • Photocatalyst Analysis Of Tio2

    development of metal oxide photocatalysts for environmentally friendly applications such as air purification [2], hydrogen production via water splitting [3] and the removal of organic molecules from water [4]. Recently, photocatalyst thin film has aroused growing interests instead of a powder type of photocatalyst. Photocatalyst film can be deposited on various substrate such as alumina [5], metal foil [6], silicon wafer [7,8], and glass [9,10]. Among these substrates, the glass can be…

    Words: 793 - Pages: 4
  • Pre-Industrial Revolution And Air Pollution

    are combustion of fossil fuels at power stations, industries and automobiles. Most of the emissions are released from the man-made sources as compared to the natural sources. “Burning of fossil fuels in industries and transport sector, industrialization and urbanization have led to increase in concentrations of gaseous and particulate pollutants in the atmosphere leading to air pollution” (Singh & Agrawal, 2008, 15). When these pollutants are released from their sources, they become caught up in…

    Words: 2224 - Pages: 9
  • Taking A Look At Acid Rain

    1.1 Introduction/ what is Acid Rain? Acid rain, or acid precipitation is a term used to describe any form of precipitation with a pH of less than 5.6. In recent years, the effects of acid rain are being experienced on a global scale with widespread environmental effects. Primarily, acid rain is caused by emissions of sulfur dioxide (SO2) and nitrogen oxides (NOx) from the combustion of fossil fuels. However, even pure rainwater is slightly acidic (pH of 5.6-6.5) due to the reaction between H2O…

    Words: 1330 - Pages: 5
  • How To Save Our Planet Essay

    We have one planet to live on. Have you ever thought of that? We only have this one giant rock, hurtling through the sky at speeds too fast for us to even comprehend; and we have nowhere else to go. Yet, we still take advantage of our home. We pollute it, mine mountains, clear-cut forests and think nothing of it. In everyday life people normally like to keep their home clean and tidy, they may buy insurance to help them buy a new one if something happens to their old one. Earth is our home, yet…

    Words: 1575 - Pages: 7
  • Decision Tree Analysis In Chemistry

    The powder do not affect the chemical structure of the magnesium in the fire extinguishing process. However, a protective coat of magnesium oxide is formed on all the surface of the magnesium as it reacts very fast with air. This layer makes it hard for it continue burning. However, in case water is used when removing the residues even after several days, the fire may reignite. The water will firstly expose the surface of the magnesium residues to reaction and react with it (magnesium) to…

    Words: 956 - Pages: 4
  • Copper Created Lab Report

    The change in the reaction mixture occurred when the temperature got to a 100˚C. The mixture had turned a very dark color. The mixture started out blue and it changed to an almost black color. The mixture was continued to heat for an additional 5 minutes and then it was cooled down to room temperature. When the reaction mixture was cooled, solids started to form on the sides of the beaker. The solids were black and chunky and there was some liquid left in the beaker. The products that were…

    Words: 1320 - Pages: 6
  • Raman Spectra Analysis

    demands of the continuous casting. In order to coordinate the properties of mold flux, many oxides are used in the mold flux – especially the similar oxides such as Na2O and Li2O, and MgO and CaO. This can micro – adjust the properties of mold flux. The distributions of silicate anionic species (Qn) were obviously different whereas the equimolar substitution of CaO for MgO (and Na2O for Li2O) are at a fixed NBO/T. The degree of polymerization of molten slag with a same NBO/T is same except the…

    Words: 1530 - Pages: 6
  • How Does Agnps Enhance Luminol Fluorescence

    Recent research shows that AgNPs enhance luminol fluorescence and chemiluminescence by acting as a catalyst with hydrogen peroxide. When AgNPs interact with hydrogen peroxide they cause the peroxide to degrade into superoxide and hydroxyl radical, which also react with luminol to form 3-aminophthalate (Equations 2-5) [13]. The further degradation of hydrogen peroxide into other reactive oxygen species promotes higher fluorescence intensity. Figure 5 shows the increased fluorescence intensity…

    Words: 920 - Pages: 4
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