Nerve growth factor

exercise is the only weapon that can defeat it. It is important to note that even though Alzheimer’s takes your memory it also does much more than that. This type of disease can change your behavior altogether changing you into a person you may have never been before. The change in behavior is noticed among those closest to you because it is the type of change that is not noticeable to the person with Alzheimer’s. According to the article by Radak, “Exercise has the capability of significantly inducing BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor) and thereby neurogenesis in the hippocampus, resulting in enhanced cognitive function. These processes are just opposite the deleterious effects of AD.” The BDNF and NGF are the pathways which were described earlier as the ones that AD is attacking. By performing exercise, the ability of these pathways to fend off AD becomes increased and in doing so it promotes the growth of other pathways enabling us to hold on to our thoughts better. By putting our bodies through physical exercise and having it repress this disease it clearly shows why this is the best deterrent. According to the article review by Paillard, Rolland, Barreto (2015), “A meta-analysis conducted in 2009 concluded that PA (physical activity) reduced the risk of developing AD (Alzheimer’s disease) by 45%.” A meta-analysis is when you take studies related to you’ve done and combine them into one. The thing to be taken away from this quote…

Topical Nerve Growth Factor (NGF) Application In an animal model the topical application of NGF to wounds and ulcers leads to a statistically significant decrease in the wound perimeter (66%) vs. controls.[8, 23, 77, 120] Clinically, topical application of NGF leads to the repair of neurotrophic corneal ulcers, recovery of corneal surface sensitivity [36, 119] and diabetic foot ulcers.[73] Basic Fibroblast Growth Factor (bFGF) Topical application of bFGF enhances the healing for operative…

Introduction The predominant disease that mutant FGFR3 (fibroblast growth factor receptor 3) gene causes is Achondroplasia. Furthermore, Achondroplasia means the absence of chondrocyte formation in bones. Additionally, the transformation of chondrocytes into bone cells is prevalent in the limbs as well as the facial bones of humans (1). Therefore, the predominant symptom of Achondroplasia is bone growth retardation and is found in the limbs as well as facial bones. The majority of people…

Some of the major factors are vascular endothelial growth factor (VEGF), Fibroblast growth factor-2 (FGF-2/bFGF), Platelet-Derived growth factor-Beta (PDGF-beta), Transforming growth factor-beta (TGF-beta). These angiogenic peptides are found to be upregulated following ischemic insults to promote micro vessel formation and brain remodeling.[1] Among these numerous endogenous angiogenic regulators, VEGF is the prototypical and most studied proangiogenic mediator in stroke.[2, 3] VEGF…

IPF fibroblasts naturally express higher levels of PDGFR and FGFR than the controls. The proliferative effects of PDFG-BB and bFGF, along with VEGF, were curtailed by the drug. MMPs are endopeptidases that degrade proteins of the ECM, and TIMP are their inhibitors. As expected, treatment enhanced the expression of pro-MMP-2 protein and repressed the expression of the TIMP-2 protein. Transforming growth factor-beta (TGF-beta) is a stimulator of collagen production and upregulates collagens in…

A nerve cell is also called a motor neuron, which is made from a cell body, an axon and axon terminals. The cell body contains a nucleus and dendrites that receive the signals and send it down the axon that is covered in myelin sheath. The axon terminals are connected to the muscles creating a neuromuscular junction. This is where the signal is relayed to the muscle. There are two groups of motor neurons: upper and lower. Upper motor neurons are those found in the brain and lower motor neurons…

The principal effect that make people continue smoking is that the drug excites neural activity and speed body functions. In other words, it makes the body feel good every time he/she smokes because the drug (cigarettes) helps keep motivated the body and feel energetic throughout the year. That is why it is really difficult a person stops smoking. Although, at the same time the drug is killing nerve cells in the brain because it has strong toxins that it can damage the nerve cells and kill them.…

know that as we age our age of motion will decrease, but it can be up to 30% as we reach our senior years. Over the year’s muscle will begin to shorten thus losing their elasticity. For seniors maintain a quality of life stretching needs to be a part of their life. Stretching can increase their joint range of motions, making daily tasks a bit easier to complete. There is no set time of schedule of when stretches should be done, but seniors should aim for 3 days a week, performing each stretch…

Polyradiculitis, otherwise known as a variant of Guillain-Barre Syndrome (GBS), is a very rare disease where the immune system attacks the spinal nerve roots. Fewer than 20,000 a year get this disease, and I was one of them. It was one day in the early April of 2001. I was a healthy three year old toddler that went from running around and climbing on furniture to not being able to walk. My mom started to notice that I wasn’t walking; but instead I was pulling myself across the floor. I also had…

Muscle Pain, Adult Muscle pain (myalgia) may be caused by many things, including: • Overuse or muscle strain, especially if you are not in shape. This is the most common cause of muscle pain. • Injury. • Bruises. • Viruses, such as the flu. • Infectious diseases. • A chronic condition that causes muscle tenderness, fatigue, and headache (fibromyalgia). • A condition, such as lupus, in which the body’s disease-fighting system attacks other organs in the body (autoimmune disease). …