Neoplasm

Targeting solid tumors - primary & metastatic - irrespective of their anatomical location in the body or pathological sub-type – and permeating drug molecules into the targeted tumor mass, will improve therapeutic outcomes and reduce life-threatening systemic toxicities induced by routinely administered chemotherapeutic regimens. Creating molecular dimension-specific temporary pores in the cell membrane using precisely computed, safe radiofrequencies (RF) from an external source, to…

There are some significant differences between the two kinds of tumor. Each kind of tumor has its own characteristics. Benign tumors cannot spread out to other parts of the body because they are capsulated by a fibrous sheath of connective tissue. Therefore, they remain at their original sites. In contrast, malignant tumors (cancers) are not capsulated, so they have the ability to metastasize through blood and lymphatic vessels in a process called metastasis (1). The result of this process is…

Worldwide, malignant glioma is the most common type of central nervous system tumor in humans, and is characterized by high morbidity and mortality rates (1). The current standard of care consists of maximal surgical resection, followed by radiotherapy with concomitant and adjuvant temozolomide. Despite this multimodal approach, median survival is limited to six months (2). This poor prognosis is mainly due to the invasive potential of malignant glioma (3). To date, the molecular mechanisms…

Sensitivity of Cancerous C.elegans with Mitochondria Dysfunction Mitophagy is a selective autophagic elimination of damaged or excessive mitochondria, especially when cells are under adverse stress. Mitophagy has been identified as the cause of various human diseases and even cancer. In recent years, researchers gradually regard mitophagy as the target for cancer treatment, although the role of mitophagy in the developmental and metabolic process of cancer is still not clear. In this…

Abstract: In this paper, we have developed a shape feature extraction of MRI brain tumor image retrieval. We used T1 weighted image of MRI brain tumor images. There are two modules: feature extraction process and classification. First, the shape features are extracted using techniques like Scale invariant feature transform (SIFT), Harris corner detection and Zernike moments. Second, the supervised learning algorithms like Deep neural network (DNN) and Extreme learning machine (ELM) are used to…

An ovarian cyst is a growth or swelling on or inside the ovary. It may be solid or filled with fluid. If it is solid, it is called a tumor. This can be frightening because it immediately brings cancer to mind, but tumor is just the medical term for any swelling. There are many types of ovarian cysts, namely, functional cysts, dermoid cysts, serous & mucinous cystadenomas, endometriomas, functional tumors, fibromas and brenner tumors. Conversely, the choice of ovarian cyst treatment used to treat…

Peripheral giant cell granulomas (PGCG) are relatively uncommon reactive exophytic lesions of the oral cavity. Such a term is also synonymous to peripheral giant cell epulis, peripheral giant cell reparative granuloma though the word reparative granulomas is now considered obsolete in modern medicine because it’s not truly reparative.4,5 Clear aetiology of PGCG still remains elusive to and what is available currently are the laid hypothesis by various scholars for example local irritation from…

In a majority of the cases, HCC is associated with the underlying chronic liver disease, and it is diagnosed in advanced stage of disease when curative treatment options are not applicable. The curative treatments include radiofrequency ablation, liver transplantation, or tumor resection.Selection of a treatment modality is based on tumor size, location, extrahepatic spread, and underlying liver function. Surgical resection or liver transplantation is the first line treatment option for early…

Ovarian cysts, are also called cystic ovarian mass. Many people might ask these questions about ovarian cysts. What is it? What are the symptoms? The treatments? How does it happen? Is there more than one type? Who gets it? Can you die from it? Is there a cure? Ovarian cysts are sacs containing or semisolid material that develop in or on the surface of an ovary. They are common and the majority are harmless. They do cause symptoms similar to ovarian tumors which can be cancerous. Some symptoms…

There are many controversies about the potential harms associated with hormonal replacement therapy. In the article, “Current breast cancer risks of hormone replacement therapy in postmenopausal women” discusses different studies and data of the relative breast cancer risks of estrogen and combined estrogen/progesterone replacement in postmenopausal women. There are many factors that play into the outcome of HRT. Studies have shown that there is a greater risk with combined estrogen/progestin…