Neoplasm

Glomus tumors are usually the benign tumor of glomus cells with immunocytochemical and structural features of smooth muscle cells [1]. The majority of cases of glomus tumor are benign but rarely they demonstrate malignant features both clinically and histologically (aka glomangiosarcoma) [2]. Glomangiosarcoma in extracutaneous sites is uncommon but few cases have been reported. Glomangiosarcoma of the heart is extremely rare due to rarity or near absence of glomus bodies in the myocardium. We…

Introduction Alzheimer’s disease and cancer are known to be very serious disorders that can cause death especially in the elderly. The prevalence of cancer is dramatically increased with age, and in contrast, Alzheimer’s disease is an age-dependent neurodegenerative disorder. Cancer is defined as a disease whereby a collection of abnormal cells divides uncontrollably by ignoring the normal principles of cell division (Hejmadi, 2010). There is known to be more than 200 types of cancers and its…

The Cancer Stem Cell Hypothesis: A Basic and Clinical Approach to Treating Glioblastoma Multiforme Introduction Glioblastoma (World Health Organization grade IV glioma; GBM) is the most prevalent and malignant primary brain tumor in adults, and it is predominantly drug and radiation resistant1. Unlike many other solid tumor types, GBM extensively invades the surrounding brain, but it rarely metastasizes to other organs. Beyond its invasive nature, there are a variety of other hallmarks of…

Intensity-Modulated Radiation Therapy One of the greatest difficulties within the field of oncology is achieving the highest probability of cure with the lowest morbidity as possible. Treatment planning and delivery technology have changed significantly since the introduction of 3D treatment planning in the 1980s (Meyer, 2011). The latest and greatest method of radiation therapy is known as intensity-modulated radiation therapy (IMRT). Intensity-modulated radiation therapy is a newer, modern…

Avastin- Uses, Side effects and its effectiveness on certain types of Cancer Cancer is a fatal disease which knows no gender or age. It can develop in every human’s body and there are many types of cancer which affect certain area of the body. Cancer develops when the process of forming new cells or dying out of the old ones is interrupted and the cells become abnormal, meaning that old cells survive when they shouldn’t and new cells are formed when they are not needed. These cells grow into…

The doctor calls with your results. You hang up the phone, still in disbelief, you hit your knees praying it isn’t so… Just that quick, your entire life has changed. The “c” word is something we never want to hear, regardless the extent of it, we always think the worse. Bone cancer is a skeletal system disease that originates within a bone of the body, causing the bone to weaken. Cancer begins when healthy cells change and grow out of control, forming a tumor. The tumor can be…

Cancer is one of the leading medical enigmas that doctors face today. It is a devastating disease that claims the lives of far too many people worldwide each year. In fact, according to the Centers for Disease Control and Prevention, 14 million people worldwide discover each year that they have cancer, and out of these 14 million, approximately 8 million people die globally from cancer. There is no doubt regarding the fact that the race to find a cure for cancer is rapidly increasing in…

Cell Cycle and Cancer By Samuel Lehew Cell Cycle and Cancer By Samuel Lehew (Rough Draft) The cell cycle is a complex set of stages where the cell duplicates itself, in which the captivating process of this is explained cancer will also be explained and how the different types of cancer can be treated differently. Also, the fatality rates and the genetic inheritability. Cancer can affect any at any moment, just one mistake in one of these stages and the mutation and uncontrolled cell growth…

What is cancer? Cancer is the normal cells in your body that become abnormal by not being able to perform the final processes of the cell cycle, apoptosis, and die. When cancer cells cannot perform this process of dying they continue to rapidly grow and multiply. Eventually they become a large growth of cells also known as a tumor. When a tumor is not harmful it is called a “benign” tumor. When a tumor is harmful and cancerous it is considered “malignant”. From there the cancer is at stage 1…

Hypoxia is a crucial feature of locally advanced solid tumors resulting from a poor oxygen supply delivery owing to excessive cellular proliferation and abnormal vascular architecture. Under these circumstances, cancer cells develop a series of responses in order to adapt to hypoxic conditions. The tumor suppressor p53 has been shown to mediate the cellular response to hypoxia depending on many contexts including cell type, duration and severity of hypoxic exposure. The sphingolipid ceramide,…